Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets

JM Leung, DD Sin - Bmj, 2017 - bmj.com
Asthma-COPD overlap syndrome (ACOS) or asthma-COPD overlap captures the subset of
patients with airways disease who have features of both asthma and chronic obstructive …

Mechanisms of airway hyper‐responsiveness in asthma: the past, present and yet to come

DG Chapman, CG Irvin - Clinical & Experimental Allergy, 2015 - Wiley Online Library
Airway hyper‐responsiveness (AHR) has long been considered a cardinal feature of
asthma. The development of the measurement of AHR 40 years ago initiated many …

Clinical characteristics of the asthma–COPD overlap syndrome–a systematic review

M Nielsen, CB Bårnes, CS Ulrik - International journal of chronic …, 2015 - Taylor & Francis
Background and objective In recent years, the so-called asthma–chronic obstructive
pulmonary disease (COPD) overlap syndrome (ACOS) has received much attention, not …

Update on asthma–COPD overlap (ACO): a narrative review

E Mekov, A Nuñez, DD Sin, M Ichinose… - … Journal of Chronic …, 2021 - Taylor & Francis
Although chronic obstructive pulmonary disease (COPD) and asthma are well-characterized
diseases, they can coexist in a given patient. The term asthma–COPD overlap (ACO) was …

Identification and definition of asthma–COPD overlap: the CanCOLD study

M Barrecheguren, L Pinto… - …, 2020 - Wiley Online Library
Background and objective Lack of consensus on diagnosis of ACO limits our understanding
of the impact, management and outcomes of ACO. The present observational study aims to …

Asthma–COPD overlap syndrome (ACOS): a diagnostic challenge

NV Tho, HY Park, Y Nakano - Respirology, 2016 - Wiley Online Library
Asthma–chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) is
characterized by persistent airflow limitation with several features usually associated with …

Understanding COPD-overlap syndromes

TY Poh, M Mac Aogáin, AKW Chan… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease accounts for a large burden of lung
disease. It can 'overlap'with other respiratory diseases including bronchiectasis, fibrosis and …

[HTML][HTML] Small airway dysfunction links asthma severity with physical activity and symptom control

M Abdo, F Trinkmann, AM Kirsten, F Pedersen… - The Journal of Allergy …, 2021 - Elsevier
Background Little is known about the role of small airway dysfunction (SAD) and its complex
relation with asthma control and physical activity (PA). Objective To investigate the …

Do we really need asthma–chronic obstructive pulmonary disease overlap syndrome?

M Cazzola, P Rogliani - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
The association of asthma and chronic obstructive pulmonary disease (COPD) in the same
patient, which is designated as mixed asthma-COPD phenotype or overlap syndrome …

Symptom burden, health status, and productivity in patients with uncontrolled and controlled severe asthma in NOVELTY

B Ding, S Chen, D Srivastava, A Quinton… - Journal of asthma …, 2023 - Taylor & Francis
Background Few studies have quantified symptom burden, health status, and productivity in
patients with uncontrolled and controlled severe asthma. Up-to-date, real-world, global …