Postoperative radiotherapy, which forms part of breastconserving therapy, may not need to
encompass the whole breast. Apart from the consumption of huge resources and patients' …

Locoregional recurrence (LRR) after therapy for early breast cancer is common. Patients
with LRR can suffer both local consequences and symptoms of metastatic disease, as LRR …

Purpose To determine the prognostic significance of triple negative breast cancers with
respect to locoregional relapse and distant metastasis in conservatively managed breast …

Purpose: The purpose of this study was to classify all ipsilateral breast tumor relapses (IBTR)
in patients treated with conservative surgery and radiation therapy (CS+ RT) as either new …

PURPOSE: Recent laboratory data suggest a role for BRCA1/2 in the cellular response to
DNA damage. There is a paucity of clinical data, however, examining the effect of …

BACKGROUND This report updated previous findings, at the 15‐year mark, of the National
Surgical Breast and Bowel Project (NSAPB) Protocol B‐06 with respect to the treatment of …

BACKGROUND The clinical features of ipsilateral breast tumor recurrence (IBTR) after
breast conserving therapy (BCT) for early stage breast cancer were analyzed from long‐term …

Abstract Using the Danish Civil Registration System, the authors identified all women under
50 years of age who were treated for cancer of the breast in Denmark between 1982 and …

BACKGROUND: Germline mutations in the BRCA1 and BRCA2 genes are associated with
an increased risk of breast cancer. Whether women with breast cancer who have inherited …

Abstract BACKGROUND Although BRCA1 and BRCA2 were identified in 1994 and 1995,
respectively, to the authors' knowledge the optimal management of women with BRCA …