The expression of B7-H3 isoforms in newly diagnosed glioblastoma and recurrence and their functional role

M Digregorio, N Coppieters, A Lombard… - Acta Neuropathologica …, 2021 - Springer
Short survival of glioblastoma (GBM) patients is due to systematic tumor recurrence. Our
laboratory identified a GBM cell subpopulation able to leave the tumor mass (TM) and …

Investigation on the effect of nanoparticle size on the blood–brain tumour barrier permeability by in situ perfusion via internal carotid artery in mice

JH Kang, J Cho, YT Ko - Journal of drug targeting, 2019 - Taylor & Francis
The blood–brain barrier (BBB) is a limiting factor in nanoparticle drug delivery to the brain,
and various attempts have been made to overcome it for efficient drug delivery. Nowadays, it …

Dual-selective photodynamic therapy with a mitochondria-targeted photosensitizer and fiber optic cannula for malignant brain tumors

JH Kang, YT Ko - Biomaterials science, 2019 - pubs.rsc.org
Among brain tumors, glioblastoma multiforme (GBM) is the most common and aggressive
form (WHO grade IV) with a median survival of only 14.6 months in adults. Photodynamic …

Highly invasive fluorescent/bioluminescent patient-derived orthotopic model of glioblastoma in mice

D Yuzhakova, E Kiseleva, M Shirmanova… - Frontiers in …, 2022 - frontiersin.org
Development of the novel diagnostic and therapeutic approaches in neuro-oncology
requires tumor models that closely reproduce the biological features of patients' tumors …

The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation

P D'Arrigo, M Digregorio, S Romano, M Tufano… - Cell Death …, 2019 - nature.com
Gliomas aberrantly express programmed cell death ligand-1 (PD-L1), which has a pivotal
role in immunoevasion. The splicing isoform of FKBP5, termed FKBP51s, is a PD-L1 foldase …

Integrin α3 mediates stemness and invasion of glioblastoma by regulating POU3F2

J Yao, L Wang - Current Protein and Peptide Science, 2023 - ingentaconnect.com
Background: Glioblastoma (GBM) is an aggressive brain tumor. Integrins have been
implicated in the malignancy of GBM. A recent study demonstrated that integrin α3 (ITGA3) …

Investigating the Role of Oncogenic H3. 3 p. K27M Mutation in Diffuse Intrinsic Pontine Glioma

EC Lubanszky - 2024 - search.proquest.com
Abstract Diffuse Intrinsic Pontine Glioma (DIPG) is a pediatric high-grade glioma that
diffusely penetrates the brainstem and is the leading cause of pediatric brain-tumour related …

Compositions and methods for treatment of central nervous system tumors

SI Svetlov - US Patent 11,434,195, 2022 - Google Patents
Compounds, pharmaceutical compositions, and methods for treating cancer, in particular
brain cancer, are provided, including amphiphilic fatty acid/alcohol ethers (AIPs) com prising …

[引用][C] Design and development of a hydrogel formulation with nanoparticles for the treatment of glioblastoma multiforme

LEC dos Santos - 2021 - University of Dublin, Ireland