JH Kang, J Cho, YT Ko - Journal of drug targeting, 2019 - Taylor & Francis
The blood–brain barrier (BBB) is a limiting factor in nanoparticle drug delivery to the brain, and various attempts have been made to overcome it for efficient drug delivery. Nowadays, it …
JH Kang, YT Ko - Biomaterials science, 2019 - pubs.rsc.org
Among brain tumors, glioblastoma multiforme (GBM) is the most common and aggressive form (WHO grade IV) with a median survival of only 14.6 months in adults. Photodynamic …
Development of the novel diagnostic and therapeutic approaches in neuro-oncology requires tumor models that closely reproduce the biological features of patients' tumors …
Gliomas aberrantly express programmed cell death ligand-1 (PD-L1), which has a pivotal role in immunoevasion. The splicing isoform of FKBP5, termed FKBP51s, is a PD-L1 foldase …
J Yao, L Wang - Current Protein and Peptide Science, 2023 - ingentaconnect.com
Background: Glioblastoma (GBM) is an aggressive brain tumor. Integrins have been implicated in the malignancy of GBM. A recent study demonstrated that integrin α3 (ITGA3) …
Abstract Diffuse Intrinsic Pontine Glioma (DIPG) is a pediatric high-grade glioma that diffusely penetrates the brainstem and is the leading cause of pediatric brain-tumour related …
SI Svetlov - US Patent 11,434,195, 2022 - Google Patents
Compounds, pharmaceutical compositions, and methods for treating cancer, in particular brain cancer, are provided, including amphiphilic fatty acid/alcohol ethers (AIPs) com prising …