Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

M Raices, MA D'angelo - Nature reviews Molecular cell biology, 2012 - nature.com
Nuclear pore complexes (NPCs) are multiprotein aqueous channels that penetrate the
nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple …

Nuclear pore complexes in development and tissue homeostasis

V Guglielmi, S Sakuma, MA D'Angelo - Development, 2020 - journals.biologists.com
Nuclear pore complexes are multiprotein channels that span the nuclear envelope, which
connects the nucleus to the cytoplasm. In addition to their main role in the regulation of …

Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis

NM Kotb, G Ulukaya, A Chavan… - Genes & …, 2024 - genesdev.cshlp.org
Genome organization can regulate gene expression and promote cell fate transitions. The
differentiation of germline stem cells (GSCs) to oocytes in Drosophila involves changes in …

Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana

V Nolte, RV Pandey, R Kofler, C Schlötterer - Genome research, 2013 - genome.cshlp.org
Although it is well understood that selection shapes the polymorphism pattern in Drosophila,
signatures of classic selective sweeps are scarce. Here, we focus on Drosophila mauritiana …

Identification of proteomic markers for ram spermatozoa motility using a tandem mass tag (TMT) approach

W Zhu, Y Zhang, C Ren, X Cheng, J Chen, Z Ge… - Journal of …, 2020 - Elsevier
Sperm motility is crucial for ram fertility; however, differences in the proteome of sperm with
high-and low-motility in rams (Ovis aries) has yet to be achieved. Thus, the aim of this study …

A feedback loop between heterochromatin and the nucleopore complex controls germ-cell-to-oocyte transition during Drosophila oogenesis

K Sarkar, NM Kotb, A Lemus, ET Martin, A McCarthy… - Developmental Cell, 2023 - cell.com
Germ cells differentiate into oocytes that launch the next generation upon fertilization. How
the highly specialized oocyte acquires this distinct cell fate is poorly understood. During …

Dynamics and diverse functions of nuclear pore complex proteins

G Chatel, B Fahrenkrog - Nucleus, 2012 - Taylor & Francis
Nuclear pore complexes (NPCs) are best known for their central role in controlling the
molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from …

Regulated nucleocytoplasmic transport during gametogenesis

Y Miyamoto, PR Boag, GR Hime… - Biochimica et Biophysica …, 2012 - Elsevier
Gametogenesis is the process by which sperm or ova are produced in the gonads. It is
governed by a tightly controlled series of gene expression events, with some common and …

The Microtubule Cytoskeleton during the Early Drosophila Spermiogenesis

MG Riparbelli, V Persico, G Callaini - Cells, 2020 - mdpi.com
Sperm elongation and nuclear shaping in Drosophila largely depends on the microtubule
cytoskeleton that in early spermatids has centrosomal and non-centrosomal origins. We …

Emerging roles for nucleoporins in reproductive cellular physiology

CC Preston, EC Storm, RJ Leonard… - Canadian journal of …, 2019 - cdnsciencepub.com
Nucleoporins are a specialized subset of nuclear proteins that comprise the nuclear pore
complex and regulate nucleocytoplasmic transport. Recent demonstrations of roles for …