Chronic kidney disease

AC Webster, EV Nagler, RL Morton, P Masson - The lancet, 2017 - thelancet.com
The definition and classification of chronic kidney disease (CKD) have evolved over time,
but current international guidelines define this condition as decreased kidney function …

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group …

J Tamargo, KP Kjeldsen, E Delpón… - European Heart …, 2022 - academic.oup.com
Population ageing has resulted in an increasing number of older people living with chronic
diseases (multimorbidity) requiring five or more medications daily (polypharmacy). Ageing …

[HTML][HTML] Global, regional, and national burden of mortality associated with short-term temperature variability from 2000–19: a three-stage modelling study

Y Wu, S Li, Q Zhao, B Wen, A Gasparrini… - The Lancet Planetary …, 2022 - thelancet.com
Background Increased mortality risk is associated with short-term temperature variability.
However, to our knowledge, there has been no comprehensive assessment of the …

[HTML][HTML] Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from …

R Pellegrino, R Paganelli, A Di Iorio, S Bandinelli… - Immunity & …, 2023 - Springer
Background Neutrophils and lymphocytes represent the larger percentage of all white blood
cells, they vary with age, with a progressive increase of the ratio in the first years of life, and …

[HTML][HTML] Glomerular filtration in the aging population

IL Noronha, GP Santa-Catharina, L Andrade… - Frontiers in …, 2022 - frontiersin.org
In the last decades, improvements in the average life expectancy in the world population
have been associated with a significant increase in the proportion of elderly people, in …

Diagnostic performance of creatinine-based equations for estimating glomerular filtration rate in adults 65 years and older

L da Silva Selistre, DL Rech, V de Souza… - JAMA internal …, 2019 - jamanetwork.com
Importance Estimating glomerular filtration rate (GFR) is useful in many clinical conditions.
However, very few studies have evaluated the performance of GFR-estimating equations in …

[HTML][HTML] Epidemiología del uso de medicamentos en el adulto mayor

F Salech, QFD Palma, QFP Garrido - Revista Médica Clínica Las Condes, 2016 - Elsevier
Los adultos mayores son importantes consumidores de fármacos. Un tercio de las
prescripciones de medicamentos son hechas en esta población. Revisiones sistemáticas de …

[HTML][HTML] Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer's disease in a …

JJ Wu, SC Weng, CK Liang, CS Lin, TH Lan, SY Lin… - BMC geriatrics, 2020 - Springer
Background Chronic kidney disease (CKD), low serum albumin, and anemia are known risk
factors for cognitive decline in older people. We investigated the association between kidney …

[HTML][HTML] Effects of Moringa oleifera aqueous leaf extract in alloxan induced diabetic mice

MJ Tuorkey - Interventional Medicine and Applied Science, 2016 - akjournals.com
Objective There is a lack of knowledge regarding the underlying mechanisms of the
antidiabetic activity of Moringa oleifera. This study investigates the antidiabetic effect of M …

Pharmacokinetics and drug metabolism of antibiotics in the elderly

F Pea - Expert Opinion on Drug Metabolism & Toxicology, 2018 - Taylor & Francis
Introduction: The number of elderly people is increasing worldwide. The elderly may be at
increased risk of bacterial infections compared with younger adults. Dosing adaptation of …