DCTPP1, an oncogene regulated by miR-378a-3p, promotes proliferation of breast cancer via DNA repair signaling pathway

M Niu, M Shan, Y Liu, Y Song, J Han, S Sun… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BRCA) is one of the most deadly cancers worldwide, with poor survival rates
that could be due to its high proliferation. Human all-alpha dCTP pyrophosphatase 1 …

Association of RAD51, XRCC1, XRCC2, and XRCC3 Polymorphisms with Risk of Breast Cancer

P Gupta, V Sambyal, K Guleria, MS Uppal… - Genetic Testing and …, 2023 - liebertpub.com
Background: DNA repair genes are among the low-penetrance genes implicated in breast
cancer. However variants of DNA repair genes may alter their protein function thus leading …

[HTML][HTML] Rare Germline Variants in DNA Repair Genes Detected in BRCA-Negative Finnish Patients with Early-Onset Breast Cancer

V Kurkilahti, VS Rathinakannan, E Nynäs, N Goel… - Cancers, 2024 - mdpi.com
Simple Summary Breast cancer is the most common cancer in females. Although rare in the
younger population, individuals with a susceptible genetic background are at higher risk of …

Involvement of ERCC1 (rs3212986) and ERCC2 (rs1799793, rs13181) polymorphisms of DNA repair genes in breast cancer occurrence in Burkina Faso

MDW Adico, AA Zouré, HK Sombié… - … Genetics & Genomic …, 2023 - Wiley Online Library
Background Genetic alterations can result in DNA repair defects, increasing susceptibility to
breast cancer. The aim of this study was to evaluate the involvement of two DNA repair …

Impact of xenobiotic-metabolizing gene polymorphisms on breast cancer risk in South Indian women

T Rajagopal, A Seshachalam, KK Rathnam… - Breast Cancer Research …, 2021 - Springer
Background Functional variants of the xenobiotic-metabolizing genes (XMG) might modulate
breast cancer (BC) risk by altering the rate of metabolism and clearance of myriad types of …

Полиморфизм гена hOGG1 и предрасположенность к злокачественным новообразованиям у людей, подвергшихся длительному облучению с низкой …

МА Янишевская, ЕА Блинова, ЕА Шишкина… - Радиационная …, 2025 - radhyg.ru
Аннотация В проведенном раннее исследовании [1] мы показали повышенный риск
развития злокачественных новообразований у носителей минорного аллеля …

The association of rs25487 of the XRCC1 gene and rs13181 of the ERCC2 gene polymorphisms with the ovarian cancer risk

T Zavarykina, M Kapralova, P Lomskova… - Biomolecules and …, 2024 - bjbms.org
Ovarian cancer (OC) is the most lethal gynecological cancer worldwide. DNA damage plays
an important role in cancer development, and the proteins encoded by XRCC1 and ERCC2 …

[PDF][PDF] Polymorphism of hOGG1 gene and susceptibility to malignant neoplasms in people affected by long-term low dose rate exposure

MA Yanishevskaya, EA Blinova, EA Shishkina… - Научно-практический …, 2024 - radhyg.ru
In the previous study [1], we showed an increased risk of malignant neoplasms in carriers of
the minor allele rs1052133* G of the hOGG1 gene who were affected by chronic radiation …

Evaluation of association studies and a systematic review and meta-analysis of XRCC1 polymorphisms in breast cancer risk

L Zhao, X Yin, J Qin, XH Ye, Y Zhou, W Wang, X He - 2022 - researchsquare.com
Background To investigate the association between XRCC1 Arg194Trp, Arg280His and
Arg399Gln polymorphisms and breast cancer (BC) risk, fifteen previous meta-analyses and …