New insights into molecular mechanisms of diabetic kidney disease

SS Badal, FR Danesh - American journal of kidney diseases, 2014 - Elsevier
Diabetic kidney disease remains a major microvascular complication of diabetes and the
most common cause of chronic kidney failure requiring dialysis in the United States. Medical …

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products

G Aldini, G Vistoli, M Stefek, N Chondrogianni… - Free radical …, 2013 - Taylor & Francis
The advanced glycoxidation end products (AGEs) and lipoxidation end products (ALEs)
contribute to the development of diabetic complications and of other pathologies. The review …

Mild cognitive impairment in type 2 diabetes mellitus and related risk factors: a review

XY Yuan, XG Wang - Reviews in the Neurosciences, 2017 - degruyter.com
Type 2 diabetes mellitus (T2DM) is a global epidemic disease and has become a significant
health problem. Many studies have raised concern about the mild cognitive impairment …

[PDF][PDF] Review of the health benefits of Faba bean (Vicia faba L.) polyphenols.

I Turco, G Ferretti, T Bacchetti - Journal of Food & Nutrition Research, 2016 - vup.sk
The dietary consumption of legumes is associated with a lower incidence of chronic
degenerative diseases. Among legumes, a growing interest is devoted to Faba bean (Vicia …

RAGE inhibitors for targeted therapy of cancer: a comprehensive review

T Faruqui, MS Khan, Y Akhter, S Khan, Z Rafi… - International Journal of …, 2022 - mdpi.com
The receptor for advanced glycation end products (RAGE) is a member of the
immunoglobulin family that is overexpressed in several cancers. RAGE is highly expressed …

Role and mechanisms of RAGE-ligand complexes and RAGE-inhibitors in cancer progression

AH El-Far, G Sroga, SK Al Jaouni… - International journal of …, 2020 - mdpi.com
Interactions of the receptor for advanced glycation end product (RAGE) and its ligands in the
context of their role in diabetes mellitus, inflammation, and carcinogenesis have been …

Current perspectives on the health risks associated with the consumption of advanced glycation end products: recommendations for dietary management

S Palimeri, E Palioura… - … metabolic syndrome and …, 2015 - Taylor & Francis
Advanced glycation end products (AGEs) constitute a complex group of compounds
produced endogenously during the aging process and under conditions of hyperglycemia …

Molecular sources of residual cardiovascular risk, clinical signals, and innovative solutions: relationship with subclinical disease, undertreatment, and poor adherence …

R Kones - Vascular Health and Risk Management, 2013 - Taylor & Francis
Residual risk, the ongoing appreciable risk of major cardiovascular events (MCVE) in statin-
treated patients who have achieved evidence-based lipid goals, remains a concern among …

Effects of RAGE-specific inhibitor FPS-ZM1 on amyloid-β metabolism and AGEs-induced inflammation and oxidative stress in rat hippocampus

Y Hong, C Shen, Q Yin, M Sun, Y Ma, X Liu - Neurochemical research, 2016 - Springer
An increased level of advanced glycation end products (AGEs) is observed in brains of
patients with Alzheimer's disease (AD). AGEs and receptor for AGEs (RAGE) play important …

Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice

H Wang, F Chen, YF Du, Y Long, MN Reed, M Hu… - …, 2018 - Elsevier
Aims To investigate restorative effects of the receptor for advanced glycation end products
(RAGE)-specific inhibitor FPS-ZM1 on abnormal amyloid β (Aβ) influx across the blood brain …