Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

Organophosphorus compounds (OP) are a constant problem, both in the military and in the
civilian field, not only in the form of acute poisoning but also for their long-lasting …

Ketamine, a nonselective NMDA receptor antagonist, is used widely in medicine as an
anesthetic agent. However, ketamine's mechanisms of action lead to widespread …

Background and Objectives Few data are available regarding the use of anesthetic infusions
for refractory status epilepticus (RSE) in children and neonates, and ketamine use is …

Status epilepticus (SE) is one of the most common neurological emergencies in children. To
date, there is no definitive evidence to guide treatment of SE refractory to benzodiazepines …

Status epilepticus causes prolonged or repetitive seizures that, if left untreated, can lead to
neuronal injury, severe disability, coma and death in paediatric and adult populations. While …

Background Status epilepticus (SE) persisting despite two anti‐seizures medications (ASM)
and anesthetics is labeled super refractory (SRSE), correlating with important morbidity and …

New-onset refractory status epilepticus (NORSE) is a clinical presentation, not a specific
diagnosis, in a patient without active epilepsy or other preexisting relevant neurologic …

Ketamine is currently being used as an anesthetic/antiepileptic drug in refractory status
epilepticus. To validate its use, 2 clinical trials are recruiting patients. However, preclinical …

Background Pediatric refractory status epilepticus (RSE) often requires management with
anesthetic infusions, but few data compare first-line anesthetics. This study aimed to …