X‐Ray‐Induced Drug Release for Cancer Therapy

H Liu, J Zhao, Y Xue, J Zhang, H Bai… - Angewandte Chemie …, 2023 - Wiley Online Library
Drug delivery systems (DDSs) are designed to deliver therapeutic agents to specific target
sites while minimizing systemic toxicity. Recent developments in drug‐loaded DDSs have …

Gadolinium loaded nanoparticles in theranostic magnetic resonance imaging

Y Liu, N Zhang - Biomaterials, 2012 - Elsevier
Theranostic magnetic resonance imaging (MRI) is now receiving a growing interest in
imaging-guided drug delivery, monitoring the treatment and personalized administration etc …

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

D Ye, AJ Shuhendler, L Cui, L Tong, SS Tee… - Nature …, 2014 - nature.com
Directed self-assembly of small molecules in living systems could enable a myriad of
applications in biology and medicine, and already this has been used widely to synthesize …

Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy

Y Wei, L Gao, L Wang, L Shi, E Wei, B Zhou, L Zhou… - Drug Delivery, 2017 - Taylor & Francis
We reported a simple polydopamine (PDA)-based surface modification method to prepare
novel targeted doxorubicin-loaded mesoporous silica nanoparticles and peptide …

Chitosan nanoparticles as a smart nanocarrier for gefitinib for tackling lung cancer: Design of experiment and in vitro cytotoxicity study

H Amin, MA Amin, SK Osman, AM Mohammed… - International Journal of …, 2023 - Elsevier
Due to its poor solubility and systemic side effects, gefitinib (Gef) has limited application in
treatment of lung cancer. In this study, we used design of experiment (DOE) tools to gain the …

Biomarkers and molecular probes for cell death imaging and targeted therapeutics

BA Smith, BD Smith - Bioconjugate chemistry, 2012 - ACS Publications
Cell death is a critically important biological process. Disruption of homeostasis, either by
excessive or deficient cell death, is a hallmark of many pathological conditions. Recent …

[HTML][HTML] Molecular imaging of apoptosis: from micro to macro

W Zeng, X Wang, P Xu, G Liu, HS Eden, X Chen - Theranostics, 2015 - ncbi.nlm.nih.gov
Apoptosis, or programmed cell death, is involved in numerous human conditions including
neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of …

[HTML][HTML] Gefitinib-loaded starch nanoparticles for battling lung cancer: Optimization by full factorial design and in vitro cytotoxicity evaluation

H Amin, SK Osman, AM Mohammed… - Saudi Pharmaceutical …, 2023 - Elsevier
Lung cancer is the number one killer among all cancer types. For decades, clinicians have
been using conventional chemotherapeutics, but they can't rely on them alone anymore …

Breast cancer targeting peptide binds keratin 1: a new molecular marker for targeted drug delivery to breast cancer

R Soudy, H Etayash, K Bahadorani… - Molecular …, 2017 - ACS Publications
The biomarkers or receptors expressed on cancer cells and the targeting ligands with high
binding affinity for biomarkers play a key role in early detection and treatment of breast …

Pharmacokinetics of protein and peptide conjugates

B Bumbaca, Z Li, DK Shah - Drug metabolism and pharmacokinetics, 2019 - Elsevier
Protein and peptide conjugates have become an important component of therapeutic and
diagnostic medicine. These conjugates are primarily designed to improve pharmacokinetics …