Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

A Dahchour - Pharmacological Research, 2022 - Elsevier
Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

[HTML][HTML] Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders

MG Rahbardar, H Hosseinzadeh - Iranian journal of basic medical …, 2020 - ncbi.nlm.nih.gov
Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the
Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an …

Modulation of neurotrophic signaling pathways by polyphenols

F Moosavi, R Hosseini, L Saso… - Drug design, development …, 2015 - Taylor & Francis
Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

[HTML][HTML] Anti-neuroinflammatory potential of natural products in attenuation of Alzheimer's disease

B Shal, W Ding, H Ali, YS Kim, S Khan - Frontiers in pharmacology, 2018 - frontiersin.org
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disorder associated
with dementia and cognitive impairment most common in elderly population. Various …

Effects of rosmarinic acid on nervous system disorders: an updated review

M Ghasemzadeh Rahbardar… - … Archives of Pharmacology, 2020 - Springer
Nowadays, the worldwide interest is growing to use medicinal plants and their active
constituents to develop new potent medicines with fewer side effects. Precise dietary …

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

T Satoh, SR McKercher, SA Lipton - Free Radical Biology and Medicine, 2013 - Elsevier
Living cells maintain a balance between oxidation and reduction, and perturbations of this
redox balance are thought to contribute to various diseases. Recent attempts to regulate …

Phytochemicals that regulate neurodegenerative disease by targeting neurotrophins: a comprehensive review

R Venkatesan, E Ji, SY Kim - BioMed research international, 2015 - Wiley Online Library
Alzheimer's disease (AD), characterized by progressive dementia and deterioration of
cognitive function, is an unsolved social and medical problem. Age, nutrition, and toxins are …

Rosmarinus officinalis L. leaf extract improves memory impairment and affects acetylcholinesterase and butyrylcholinesterase activities in rat brain

M Ozarowski, PL Mikolajczak, A Bogacz… - Fitoterapia, 2013 - Elsevier
Rosmarinus officinalis L. leaf as part of a diet and medication can be a valuable proposal for
the prevention and treatment of dementia. The aim of the study was to assess the effects of …

Green tea (−) epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia

R Biasibetti, AC Tramontina, AP Costa, MF Dutra… - Behavioural brain …, 2013 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. Intracerebroventricular
(ICV) infusion of streptozotocin (STZ) provides a relevant animal model of chronic brain …

Rosmarinus officinalis polyphenols produce anti-depressant like effect through monoaminergic and cholinergic functions modulation

K Sasaki, A El Omri, S Kondo, J Han, H Isoda - Behavioural Brain Research, 2013 - Elsevier
Rosmarinus officinalis (R. officinalis), a culinary aromatic and medicinal plant, is very rich in
polyphenols and flavonoids with high antioxidant properties. This plant was reported to exert …