The water transport system in astrocytes–Aquaporins

Z Zhou, J Zhan, Q Cai, F Xu, R Chai, K Lam, Z Luan… - Cells, 2022 - mdpi.com
Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

[HTML][HTML] Aquaporins are multifunctional water and solute transporters highly divergent in living organisms

D Gomes, A Agasse, P Thiébaud, S Delrot… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Aquaporins (AQPs) are ubiquitous membrane proteins whose identification, pioneered by
Peter Agre's team in the early nineties, provided a molecular basis for transmembrane water …

[HTML][HTML] IL-7-induced glycerol transport and TAG synthesis promotes memory CD8+ T cell longevity

G Cui, MM Staron, SM Gray, PC Ho, RA Amezquita… - Cell, 2015 - cell.com
Memory T cells are critical for long-term immunity against reinfection and require interleukin-
7 (IL-7), but the mechanisms by which IL-7 controls memory T cell survival, particularly …

Aquaporin water channels in mammals

K Ishibashi, S Hara, S Kondo - Clinical and experimental nephrology, 2009 - Springer
Abstract Water channels, aquaporins (AQPs), are a family of small integral plasma
membrane proteins that primarily transport water across the plasma membrane. There are …

Water movements in the brain: role of aquaporins

MJ Tait, S Saadoun, BA Bell… - TRENDS in …, 2008 - cell.com
About 80% of the brain is water. This review discusses the importance of the three brain
water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is expressed in the …

[HTML][HTML] Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression

SJ Lee, CT Murphy, C Kenyon - Cell metabolism, 2009 - cell.com
Many studies have addressed the effect of dietary glycemic index on obesity and diabetes,
but little is known about its effect on life span itself. We found that adding a small amount of …

A current view of the mammalian aquaglyceroporins

A Rojek, J Praetorius, J Frøkiaer, S Nielsen… - Annu. Rev …, 2008 - annualreviews.org
The discovery of aquaporin water channels by Agre and coworkers answered a long-
standing biophysical question of how the majority of water crosses biological membranes …

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis… - Cell, 2012 - cell.com
Most studies on TCF7L2 SNP variants in the pathogenesis of type 2 diabetes (T2D) focus on
a role of the encoded transcription factor TCF4 in β cells. Here, a mouse genetics approach …

Insulin-and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3K/Akt/mTOR signaling cascade

A Rodríguez, V Catalan… - The Journal of …, 2011 - academic.oup.com
Objective: Glycerol constitutes an important metabolite for the control of lipid accumulation
and glucose homeostasis. The impact of obesity and obesity-associated type 2 diabetes as …

Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells

S Watanabe, CS Moniaga, S Nielsen… - Biochemical and …, 2016 - Elsevier
Abstract Aquaporin (AQP) 9, a member of the transmembrane water channel family, is
defined as a water/glycerol transporting protein. Some AQPs including AQP3 and AQP8 …