Purpose A number of studies have investigated the relationship between microsatellite
instability (MSI) and colorectal cancer (CRC) prognosis. Although many have reported a …

Aims Theoretically, bioresorbable vascular scaffolds (BVSs) may provide superior long-term
results compared with permanent metallic drug-eluting stents (DESs). However, whether …

Background In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the
monoclonal antibodies casirivimab and imdevimab, reduced the viral load and number of …

Background Electroconvulsive therapy (ECT) and subanesthetic intravenous ketamine are
both currently used for treatment-resistant major depression, but the comparative …

Background: There are no randomized data evaluating the safety or efficacy of apixaban for
stroke prevention in patients with end-stage kidney disease on hemodialysis and with atrial …

Background & aims Novel, effective treatments for Helicobacter pylori infection are needed.
This study evaluated the efficacy of vonoprazan, a potassium-competitive acid blocker, vs …

Background Peanut allergy, for which there are no approved treatment options, affects
patients who are at risk for unpredictable and occasionally life-threatening allergic reactions …

Background Limited evidence exists to show that adding a third agent to platinum-doublet
chemotherapy improves efficacy in the first-line advanced non-small-cell lung cancer …

Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

Background Dual antiplatelet therapy is recommended after coronary stenting to prevent
thrombotic complications, yet the benefits and risks of treatment beyond 1 year are …