Trends in the development of miRNA bioinformatics tools
L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …
recognition of cognate sequences and interference of transcriptional, translational or …
Therapeutic targeting of microRNAs: current status and future challenges
Z Li, TM Rana - Nature reviews Drug discovery, 2014 - nature.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that have crucial
roles in regulating gene expression. Increasing evidence supports a role for miRNAs in …
roles in regulating gene expression. Increasing evidence supports a role for miRNAs in …
Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non …
L Shi, W Zhu, Y Huang, L Zhuo, S Wang… - Clinical and …, 2022 - Wiley Online Library
Abstract Background Cancer‐associated fibroblasts (CAFs) contributes to overall tumor
progression. In the current survey, we explored the ability of microRNA‐20a (miR‐20a) …
progression. In the current survey, we explored the ability of microRNA‐20a (miR‐20a) …
Cobomarsen, an oligonucleotide inhibitor of miR‐155, co‐ordinately regulates multiple survival pathways to reduce cellular proliferation and survival in cutaneous T …
AG Seto, X Beatty, JM Lynch… - British journal of …, 2018 - Wiley Online Library
Summary miR‐155, a microRNA associated with poor prognosis in lymphoma and
leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most …
leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
[HTML][HTML] MicroRNAs: synthesis, mechanism, function, and recent clinical trials
MicroRNAs (miRNAs) are a class of small, endogenous RNAs of 21–25 nucleotides (nts) in
length. They play an important regulatory role in animals and plants by targeting specific …
length. They play an important regulatory role in animals and plants by targeting specific …
[HTML][HTML] MicroRNAs: target recognition and regulatory functions
DP Bartel - cell, 2009 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
Genetic variation in microRNA networks: the implications for cancer research
Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …
how their deregulation can lead to cancer. More recently, it has been proposed that the …
The functions of animal microRNAs
V Ambros - Nature, 2004 - nature.com
MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
[HTML][HTML] MicroRNAs: genomics, biogenesis, mechanism, and function
DP Bartel - cell, 2004 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 22 nt RNAs that can play important regulatory
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
roles in animals and plants by targeting mRNAs for cleavage or translational repression …