Strontium (Sr) is a trace element taken with nutrition and found in bone in close connection
to native hydroxyapatite. Sr is involved in a dual mechanism of coupling the stimulation of …

In the last 2 decades, Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has
gained significant prominence as a powerful imaging technique in the field of life sciences …

Vital pulp therapy (VPT) is considered a conservative treatment for preserving pulp viability
in caries‐induced dental pulp infections. However, bacterial contamination negatively affects …

Osteomyelitis is a hard-to-treat infection of the bone and bone marrow that is mainly caused
by Staphylococcus aureus, with an increasing incidence of methicillin-resistant S. aureus …

Nanohydroxyapatite (nanoHA) is the major mineral component of bone. It is highly
biocompatible, osteoconductive, and forms strong bonds with native bone, making it an …

Bone tissue engineering (BTE) aims to promote bone regeneration by means of the
synergistic effect of biomaterials, cells, and other factors, as potential alternative to …

The purpose of this Tutorial is to highlight the suitability of time-of-flight secondary ion mass
spectrometry (ToF-SIMS) and OrbiTrap™ SIMS (Orbi-SIMS) in bone research by introducing …

Calcium phosphate nanoparticles are highly biocompatible and biodegradable in bone
regeneration. On the other hand, strontium and magnesium enhance the formation of bone …

Strontium (Sr2+) ions are an effective therapeutic agent for the healing of osteoporotic bone
fractures and are therefore used, for example, in form of strontium-modified bone cements. In …

The in vitro evaluation of 3D scaffolds for bone tissue engineering in mono-cultures is a
common practice; however, it does not represent the native complex nature of bone tissue …