Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours

X Yu, Y Bai, B Han, M Ju, T Tang… - Journal of …, 2022 - Wiley Online Library
Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and
severely limits psychosocial function and quality of life, but no effective medication is …

Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding

M Blumer, T Brown, MB Freitas, AL Destro… - Science …, 2022 - science.org
Vampire bats are the only mammals that feed exclusively on blood. To uncover genomic
changes associated with this dietary adaptation, we generated a haplotype-resolved …

Heterologous Expression of Recombinant Human Cytochrome P450 (CYP) in Escherichia coli: N-Terminal Modification, Expression, Isolation, Purification, and …

T Shang, CM Fang, CE Ong, Y Pan - BioTech, 2023 - mdpi.com
Cytochrome P450 (CYP) enzymes play important roles in metabolising endogenous and
xenobiotic substances. Characterisations of human CYP proteins have been advanced with …

Association of physical activity with bioactive lipids and cardiovascular events

RA Hoshi, Y Liu, H Luttmann-Gibson, S Tiwari… - Circulation …, 2022 - Am Heart Assoc
Background: To clarify the mechanisms underlying physical activity (PA)-related
cardioprotection, we examined the association of PA with plasma bioactive lipids (BALs) and …

Downregulation of CYP39A1 serves as a novel biomarker in hepatocellular carcinoma with worse clinical outcome

D Li, T Yu, J Hu, J Wu, S Feng, Q Xu… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. CYP39A1 is a poorly characterized metabolic enzyme that has been
investigated in a few tumors. However, the role of CYP39A1 in hepatocellular carcinoma …

Oncogenomics and CYP450 Implications in Personalized Cancer Therapy

GK Udayaraja, IA Emerson - Current Pharmacogenomics and …, 2020 - ingentaconnect.com
Background: The Human Genome Project has unleashed the power of genomics in clinical
practice as a choice of individualized therapy, particularly in cancer treatment …

[引用][C] Heterologous Expression of Recombinant Human Cytochrome P450 (CYP) in Escherichia coli: N-Terminal Modification, Expression, Isolation, Purification, and …

T Shang, CM Fang, CE Ong, Y Pan - 2023 - europepmc.org
Cytochrome P450 (CYP) enzymes play important roles in metabolising endogenous and
xenobiotic substances. Characterisations of human CYP proteins have been advanced with …