The immunology of Epstein-Barr virus–induced disease

GS Taylor, HM Long, JM Brooks… - Annual review of …, 2015 - annualreviews.org
Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …

Progress and problems in understanding and managing primary Epstein-Barr virus infections

OA Odumade, KA Hogquist… - Clinical microbiology …, 2011 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a gammaherpesvirus that infects a large fraction of the human
population. Primary infection is often asymptomatic but results in lifelong infection, which is …

Distinguishing features of Long COVID identified through immune profiling

J Klein, J Wood, JR Jaycox, RM Dhodapkar, P Lu… - Nature, 2023 - nature.com
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …

[HTML][HTML] Serological diagnosis of Epstein-Barr virus infection: Problems and solutions

M De Paschale, P Clerici - World journal of virology, 2012 - ncbi.nlm.nih.gov
Serological tests for antibodies specific for Epstein-Barr virus (EBV) antigens are frequently
used to define infection status and for the differential diagnosis of other pathogens …

Cellular responses to viral infection in humans: lessons from Epstein-Barr virus

AD Hislop, GS Taylor, D Sauce… - Annu. Rev. Immunol …, 2007 - annualreviews.org
Epstein-Barr virus (EBV) provides a useful model to study cellular immunity to a genetically
stable, persistent human virus. Different sets of proteins expressed during EBV's lytic and …

Role for early-differentiated natural killer cells in infectious mononucleosis

T Azzi, A Lünemann, A Murer, S Ueda… - Blood, The Journal …, 2014 - ashpublications.org
A growing body of evidence suggests that the human natural killer (NK)-cell compartment is
phenotypically and functionally heterogeneous and is composed of several differentiation …

Laboratory assays for Epstein-Barr virus-related disease

ML Gulley, W Tang - The Journal of molecular diagnostics, 2008 - Elsevier
Epstein-Barr virus (EBV) infects various cell types in a wide spectrum of benign and
malignant diseases. Laboratory tests for EBV have improved and are increasingly used in …

The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output

V Hadinoto, M Shapiro, CC Sun… - PLoS …, 2009 - journals.plos.org
To develop more detailed models of EBV persistence we have studied the dynamics of virus
shedding in healthy carriers. We demonstrate that EBV shedding into saliva is continuous …

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

T Strowig, C Gurer, A Ploss, YF Liu, F Arrey… - Journal of Experimental …, 2009 - rupress.org
Many pathogens that cause human disease infect only humans. To identify the mechanisms
of immune protection against these pathogens and also to evaluate promising vaccine …

Epstein-Barr virus and its association with disease-a review of relevance to general practice

A Fugl, CL Andersen - BMC family practice, 2019 - Springer
Background General practitioners encounter the vast majority of patients with Epstein-Barr
virus-related disease, ie infectious mononucleosis in children and adolescents. With the …