Promotion of good mental health in young people with and without mental disorders has
received little empirical research attention and interventions for improving mental health in …

Background Prenatal and perinatal insults are implicated in the aetiopathogenesis of
psychotic disorders but the consistency and magnitude of their associations with psychosis …

Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …

Challenges associated with operationalising services for the at-risk mental state for
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …

Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

Intervention at the earliest illness stage, in ultra or clinical high-risk individuals, or indicated
prevention, currently represents the most promising strategy to ameliorate, delay or prevent …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

Psychotic disorders such as schizophrenia are heterogeneous and often debilitating
conditions that contribute substantially to the global burden of disease. The introduction of …

The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes
misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of …

Background: Indicated primary prevention in young people at Clinical High Risk for
Psychosis (CHR-P) is a promising avenue for improving outcomes of one of the most severe …