Chitosan-based nanomaterials for drug delivery

J Li, C Cai, J Li, J Li, J Li, T Sun, L Wang, H Wu, G Yu - Molecules, 2018 - mdpi.com
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …

Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome

Y Lee, N Kamada, JJ Moon - Advanced drug delivery reviews, 2021 - Elsevier
The gastrointestinal tract (GIT) affects not only local diseases in the GIT but also various
systemic diseases. Factors that can affect the health and disease of both GIT and the human …

Chemical surface modification of polymeric biomaterials for biomedical applications

W Sun, W Liu, Z Wu, H Chen - Macromolecular Rapid …, 2020 - Wiley Online Library
This review focuses on the attachment of polymer brushes to polymeric biomaterial
substrates by chemical surface modification methods for biomedical applications. In the first …

Chitosan and its derivatives as polymeric anti-viral therapeutics and potential anti-SARS-CoV-2 nanomedicine

RSL Tan, P Hassandarvish, CF Chee, LW Chan… - Carbohydrate …, 2022 - Elsevier
The coronavirus pandemic, COVID-19 has a global impact on the lives and livelihoods of
people. It is characterized by a widespread infection by the severe acute respiratory …

Challenges and strategies in drug delivery systems for treatment of pulmonary infections

DK Ho, BLB Nichols, KJ Edgar, X Murgia… - European journal of …, 2019 - Elsevier
Inhalation therapy has been reported as the most effective treatment for respiratory bacterial
infections due to the increasing relevance of drug bioavailability. Drug delivery systems …

Chitosan functionalization: Covalent and non-covalent interactions and their characterization

L Nicolle, CMA Journot, S Gerber-Lemaire - Polymers, 2021 - mdpi.com
Chitosan (CS) is a natural biopolymer that has gained great interest in many research fields
due to its promising biocompatibility, biodegradability, and favorable mechanical properties …

Models using native tracheobronchial mucus in the context of pulmonary drug delivery research: composition, structure and barrier properties

BC Huck, X Murgia, S Frisch, M Hittinger… - Advanced Drug Delivery …, 2022 - Elsevier
Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …

[PDF][PDF] Chitin, chitinases and chitin derivatives in biopharmaceutical, agricultural and environmental perspective

R Singh, SK Upadhyay, M Singh… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Chitin is a major structural polysaccharide after cellulose and exists as the most abundant
polymer in nature. Chitin is a nitrogen-containing homopolymer of β-(1, 4) linked N …

Macro-and microrheological properties of mucus surrogates in comparison to native intestinal and pulmonary mucus

BC Huck, O Hartwig, A Biehl, K Schwarzkopf… - …, 2019 - ACS Publications
Mucus is a complex hydrogel that acts as a protective barrier in various parts of the human
body. Both composition and structural properties play a crucial role in maintaining barrier …

Squalenyl hydrogen sulfate nanoparticles for simultaneous delivery of tobramycin and an alkylquinolone quorum sensing inhibitor enable the eradication of P …

DK Ho, X Murgia, C De Rossi, R Christmann… - Angewandte …, 2020 - Wiley Online Library
Elimination of pulmonary Pseudomonas aeruginosa (PA) infections is challenging to
accomplish with antibiotic therapies, mainly due to resistance mechanisms. Quorum sensing …