Background: The treatment of microtia or acquired ear deformities by surgery is a significant
challenge for plastic and ENT surgeons; one of the most difficult points is constructing the …

Congenital microtia is the most common cause of auricular defects, with a prevalence of
approximately 5.18 per 10,000 individuals. Autologous rib cartilage grafting is the leading …

The 5-year overall survival rate remains approximately 50% for head and neck (H&N)
cancer patients, even though new cancer drugs have been approved for clinical use since …

A major challenge to the clinical translation of tissue‐engineered ear scaffolds for ear
reconstruction is the limited auricular chondrocyte (hAuC) yield available from patients …

Purpose Deformities of the external ear can affect psychosocial well-being and hearing.
Current gold-standard reconstructive treatment is autologous costal cartilage grafting …

Background Cysteine‐rich protein 2 (CSRP2) is discovered as oncogene. The study aims to
investigate the clinical significance and potential mechanism of CSRP2 in head and neck …

External ear deformities can be inherited in the form of microtia and anotia, or acquired in
the case of trauma, burns or following excision of skin cancers [1, 2]. The resulting cosmetic …