Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …

During the past decade, major advances have been made in vitamin D research that
transcend the simple concept that vitamin D is important for the prevention of rickets in …

Recent evidence suggests that vitamin D intakes above current recommendations may be
associated with better health outcomes. However, optimal serum concentrations of 25 …

The aim of this study is to determine and critically evaluate the plausible relationships of
vitamin D with extra-skeletal tissues in humans. Severe vitamin D deficiency results in rickets …

Vitamin D sufficiency is required for optimal health. The conditions with strong evidence for a
protective effect of vitamin D include several bone diseases, muscle weakness, more than a …

Global high prevalence of vitamin D insufficiency and re-emergence of rickets and the
growing scientific evidence linking low circulating 25-hydroxyvitmain D to increased risk of …

BACKGROUND: Previous studies, such as the Women's Health Initiative, have shown that a
low dose of vitamin D did not protect against colorectal cancer, yet a meta-analysis indicates …

Background: In recent years, the relevance of vitamin D receptor (VDR) gene restriction
fragment length polymorphisms for various types of cancer has been investigated by a great …

The incidence and prevalence of vitamin D deficiency are increasing worldwide. It is
estimated that over 50% of the world's population have low vitamin D (ie, hypovitaminosis D; …

In many cells throughout the body, vitamin D is converted into its active form calcitriol and
binds to the vitamin D receptor (VDR), which functions as a transcription factor to regulate …