VEGF in signaling and disease: beyond discovery and development

RS Apte, DS Chen, N Ferrara - Cell, 2019 - cell.com
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …

[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Retinal vasculature development in health and disease

S Selvam, T Kumar, M Fruttiger - Progress in retinal and eye research, 2018 - Elsevier
Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

[HTML][HTML] Vascularisation of the central nervous system

M Tata, C Ruhrberg, A Fantin - Mechanisms of development, 2015 - Elsevier
The developing central nervous system (CNS) is vascularised through the angiogenic
invasion of blood vessels from a perineural vascular plexus, followed by continued sprouting …

The novel role of lymphatic vessels in the pathogenesis of ocular diseases

T Clahsen, K Hadrian, M Notara, SL Schlereth… - Progress in Retinal and …, 2023 - Elsevier
Historically, the eye has been considered as an organ free of lymphatic vessels. In recent
years, however, it became evident, that lymphatic vessels or lymphatic-like vessels …

The role of the semaphorins in cancer

G Neufeld, Y Mumblat, T Smolkin… - Cell Adhesion & …, 2016 - Taylor & Francis
The semaphorins were initially characterized as axon guidance factors, but have
subsequently been implicated also in the regulation of immune responses, angiogenesis …

[HTML][HTML] Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome …

MM Koczorowska, S Tholen, F Bucher, L Lutz… - Molecular …, 2016 - Elsevier
Cancer associated fibroblasts (CAFs) constitute an abundant stromal component of most
solid tumors. Fibroblast activation protein (FAP) α is a cell surface protease that is expressed …

Semaphorins in angiogenesis and autoimmune diseases: therapeutic targets?

V Iragavarapu-Charyulu, E Wojcikiewicz… - Frontiers in …, 2020 - frontiersin.org
The axonal guidance molecules, semaphorins, have been described to function both
physiologically and pathologically outside of the nervous system. In this review, we focus on …

Emerging insights and interventions for diabetic retinopathy

A Honasoge, E Nudleman, M Smith… - Current diabetes …, 2019 - Springer
Abstract Purpose of Review To introduce recent advances in the understanding of diabetic
retinopathy and to summarize current and emerging strategies to treat this common and …

[HTML][HTML] Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy

K Ishikawa, S Yoshida, Y Kobayashi… - … & visual science, 2015 - tvst.arvojournals.org
Methods.: Six FVMs were surgically removed from patients with proliferative diabetic
retinopathy (PDR) during pars plana vitrectomy with membrane peeling. The FVMs were …