Membrane curvature in cell biology: An integration of molecular mechanisms
IK Jarsch, F Daste, JL Gallop - Journal of Cell Biology, 2016 - rupress.org
Curving biological membranes establishes the complex architecture of the cell and mediates
membrane traffic to control flux through subcellular compartments. Common molecular …
membrane traffic to control flux through subcellular compartments. Common molecular …
Arf GAPs and membrane traffic
Z Nie, PA Randazzo - Journal of cell science, 2006 - journals.biologists.com
The selective transfer of material between membrane-delimited organelles is mediated by
protein-coated vesicles. In many instances, formation of membrane trafficking intermediates …
protein-coated vesicles. In many instances, formation of membrane trafficking intermediates …
[HTML][HTML] Structural basis for cargo regulation of COPII coat assembly
Using cryo-electron microscopy, we have solved the structure of an icosidodecahedral
COPII coat involved in cargo export from the endoplasmic reticulum (ER) coassembled from …
COPII coat involved in cargo export from the endoplasmic reticulum (ER) coassembled from …
[HTML][HTML] Synaptojanin 1-mediated PI (4, 5) P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission
B Chang-Ileto, SG Frere, RB Chan, SV Voronov… - Developmental cell, 2011 - cell.com
Summary Phosphatidylinositol-4, 5-bisphosphate [PI (4, 5) P 2] plays a fundamental role in
clathrin-mediated endocytosis. However, precisely how PI (4, 5) P 2 metabolism is spatially …
clathrin-mediated endocytosis. However, precisely how PI (4, 5) P 2 metabolism is spatially …
GTPases involved in vesicular trafficking: structures and mechanisms
Several types of GTPases play important roles in intracellular vesicular transport. These
include the Rab and Arf families of the Ras superfamily, which are key regulators of several …
include the Rab and Arf families of the Ras superfamily, which are key regulators of several …
A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility
Regulated cell polarity is central to many cellular processes. We investigated the
mechanisms that govern the rapid switching of cell polarity (reversals) during motility of the …
mechanisms that govern the rapid switching of cell polarity (reversals) during motility of the …
The multiple activities of CtBP/BARS proteins: the Golgi view
The C terminal-binding protein (CtBP) family functions in the nucleus as co-repressors of
transcription and has a crucial role in differentiation, apoptosis, oncogenesis and …
transcription and has a crucial role in differentiation, apoptosis, oncogenesis and …
Arf family GTP loading is activated by, and generates, positive membrane curvature
R Lundmark, GJ Doherty, Y Vallis, BJ Peter… - Biochemical …, 2008 - portlandpress.com
Small G-proteins belonging to the Arf (ADP-ribosylation factor) family serve as regulatory
proteins for numerous cellular processes through GTP-dependent recruitment of effector …
proteins for numerous cellular processes through GTP-dependent recruitment of effector …
Arl1p regulates spatial membrane organization at the trans-Golgi network through interaction with Arf-GEF Gea2p and flippase Drs2p
ADP ribosylation factors (Arfs) are the central regulators of vesicle trafficking from the Golgi
complex. Activated Arfs facilitate vesicle formation through stimulating coat assembly …
complex. Activated Arfs facilitate vesicle formation through stimulating coat assembly …
Early stages of Golgi vesicle and tubule formation require diacylglycerol
L Asp, F Kartberg, J Fernandez-Rodriguez… - Molecular biology of …, 2009 - Am Soc Cell Biol
We have investigated the role for diacylglycerol (DAG) in membrane bud formation in the
Golgi apparatus. Addition of propranolol to specifically inhibit phosphatidate …
Golgi apparatus. Addition of propranolol to specifically inhibit phosphatidate …