Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …

Recently, DNA nanostructures with vast application potential in the field of biomedicine,
especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have …

Over the past four decades, the field of structural DNA nanotechnology has evolved into an
accessible approach to generating DNA nanostructures with precise control of size …

With the rapid development of DNA nanotechnology, various DNA nanostructures with
different shapes and sizes have been self-assembled using “bottom-up” fabrication …

Rapid and precise in situ detection of gene expressions within a single cell is highly
informative and offers valuable insights into its state. Detecting mRNA within single cells in …

The protein corona is a protein layer formed on the surface of nanoparticles administered in
vivo and considerably affects the in vivo fate of nanoparticles. Although it is challenging to …

Nanoparticle delivery systems have been extensively investigated for targeted delivery of
anticancer drugs over the past decades. However, it is still a great challenge to overcome …

ABSTRACT RNA-based therapeutics are emerging as a powerful platform for the treatment
of multiple diseases. Currently, the two main categories of nucleic acid therapeutics …