The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP
metabolism through which more than 95% of TRP is catabolized. The pathway is activated …

Neurodegenerative diseases are multifactorial, initiated by a series of the causative complex
which develops into a certain clinical picture. The pathogenesis and disease course vary …

Depression, anxiety, and dementia are spectra of the most common symptoms experienced
by patients with a wide range of diseases. The symptoms often concur and frequently wax …

During the past decade, the field of human–animal interaction (s) research has been
characterized by a significant increase in scientific findings. These data have contributed to …

Psychotherapy is a comprehensive biological treatment modifying complex underlying
cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with …

Background Non-pharmacological interventions are considered the first-line treatment for
managing the behavioral and psychological symptoms of dementia. Given the …

Chronic pain is an unpleasant sensory and emotional experience that persists or recurs
more than three months and may extend beyond the expected time of healing. Recently …

Background Socially assistive robots offer an alternate source of connection for interventions
within health and social care amidst a landscape of technological advancement and …

Background Systematic reviews suggest that animal-assisted therapy (AAT) and pet-robot
interventions (PRI) achieve a reduction in mental health variables such as depressive …

Introduction The aging of the population and the high incidence of those over 80 lead to an
inevitable increase in chronic degenerative diseases, such as dementia, resulting in …