[HTML][HTML] Chromatin modules and their implication in genomic organization and gene regulation
G van Mierlo, O Pushkarev, JF Kribelbauer… - Trends in Genetics, 2023 - cell.com
Regulation of gene expression is a complex but highly guided process. While genomic
technologies and computational approaches have allowed high-throughput mapping of cis …
technologies and computational approaches have allowed high-throughput mapping of cis …
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
Genome-wide association studies (GWASs) have uncovered hundreds of autoimmune
disease-associated loci; however, the causal genetic variants within each locus are mostly …
disease-associated loci; however, the causal genetic variants within each locus are mostly …
Pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic mitofusin 2 mutations
AL Yenkin, JC Bramley, CL Kremitzki… - Communications …, 2022 - nature.com
Most human genetic variation is classified as variants of uncertain significance. While
advances in genome editing have allowed innovation in pooled screening platforms, many …
advances in genome editing have allowed innovation in pooled screening platforms, many …
Investigations into the Adaptive Value and Biological Consequences of Positively-Selected Neanderthal Introgressed Genetic Variation in Modern Humans
E Jagoda - 2021 - search.proquest.com
The sequencing of ancient genomes has revealed that modern humans interbred with at
least two different archaic hominin populations, Neanderthals and Denisovans. Some of this …
least two different archaic hominin populations, Neanderthals and Denisovans. Some of this …
Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen
AL Yenkin, JC Bramley, CL Kremitzki, JE Waligorski… - bioRxiv, 2021 - biorxiv.org
Most human genetic variation is classified as VUS-variants of uncertain significance. While
advances in genome editing have allowed innovation in pooled screening platforms, many …
advances in genome editing have allowed innovation in pooled screening platforms, many …
[图书][B] Discovery of novel functional sequences through the analysis of tiling CRISPR screens
PC Fiaux - 2021 - search.proquest.com
UNIVERSITY OF CALIFORNIA SAN DIEGO Discovery of novel functional sequences through
the analysis of tiling CRISPR screens A disse Page 1 UNIVERSITY OF CALIFORNIA SAN …
the analysis of tiling CRISPR screens A disse Page 1 UNIVERSITY OF CALIFORNIA SAN …