L‐lysine: its antagonism with L‐arginine in controlling viral infection. Narrative literature review
MC Pedrazini, MH da Silva… - British Journal of Clinical …, 2022 - Wiley Online Library
Knowledge about viral characteristics, mechanisms of entry into the host cell and
multiplication/dissemination can help in the control and treatment of viral pathologies …
multiplication/dissemination can help in the control and treatment of viral pathologies …
Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7 …
T Weitao, G Grandinetti, P Guo - Exploration, 2023 - Wiley Online Library
Investigations of the parallel architectures of biomotors in both prokaryotic and eukaryotic
systems suggest a similar revolving mechanism in the use of ATP to drive translocation of …
systems suggest a similar revolving mechanism in the use of ATP to drive translocation of …
Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity
The conjoining of salient pharmacophoric properties directing the development of prominent
cytotoxic agents was executed by constructing thiadiazolo-carboxamide bridged β-carboline …
cytotoxic agents was executed by constructing thiadiazolo-carboxamide bridged β-carboline …
Sub-stoichiometric Modulation of Viral Targets─ Potent Antiviral Agents That Exploit Target Vulnerability
NA Meanwell - ACS Medicinal Chemistry Letters, 2023 - ACS Publications
The modulation of oligomeric viral targets at sub-stoichiometric ratios of drug to target has
been advocated for its efficacy and potency, but there are only a limited number of …
been advocated for its efficacy and potency, but there are only a limited number of …
Mutual interplay between the human cytomegalovirus terminase subunits pUL51, pUL56, and pUL89 promotes terminase complex formation
S Neuber, K Wagner, T Goldner, P Lischka… - Journal of …, 2017 - Am Soc Microbiol
Human cytomegalovirus (HCMV) genome encapsidation requires several essential viral
proteins, among them pUL56, pUL89, and the recently described pUL51, which constitute …
proteins, among them pUL56, pUL89, and the recently described pUL51, which constitute …
Controlling the revolving and rotating motion direction of asymmetric hexameric nanomotor by arginine finger and channel chirality
Nanomotors in nanotechnology are as important as engines in daily life. Many ATPases are
nanoscale biomotors classified into three categories based on the motion mechanisms in …
nanoscale biomotors classified into three categories based on the motion mechanisms in …
An arginine finger regulates the sequential action of asymmetrical hexameric ATPase in the double-stranded DNA translocation motor
Z Zhao, GM De-Donatis, C Schwartz… - … and Cellular Biology, 2016 - Taylor & Francis
Biological motors are ubiquitous in living systems. Currently, how the motor components
coordinate the unidirectional motion is elusive in most cases. Here, we report that the …
coordinate the unidirectional motion is elusive in most cases. Here, we report that the …
Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents
VP Krasnov, VL Andronova, AV Belyavsky… - Molecules, 2023 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is an extremely widespread pathogen characterized by
recurrent infections. HSV-1 most commonly causes painful blisters or sores around the …
recurrent infections. HSV-1 most commonly causes painful blisters or sores around the …
High resolution structure of hexameric herpesvirus DNA-packaging motor elucidates revolving mechanism and ends 20-year fervent debate
P Guo - Protein & Cell, 2020 - academic.oup.com
In this issue of the Protein & Cell Journal, a research team (from Institute of Biophysics,
Chinese Academy of Sciences) led by professors Xiangxi Wang and Zihe Rao report the …
Chinese Academy of Sciences) led by professors Xiangxi Wang and Zihe Rao report the …
The C-terminal part of the human cytomegalovirus terminase subunit pUL51 is central for terminase complex assembly
S Neuber, K Wagner, M Messerle… - Journal of General …, 2018 - microbiologyresearch.org
The cleavage and packaging of the human cytomegalovirus (HCMV) genome is
accomplished by the viral terminase, comprising pUL56 and pUL89, and the recently …
accomplished by the viral terminase, comprising pUL56 and pUL89, and the recently …