Lyme disease pathogenesis

J Coburn, B Garcia, LT Hu, MW Jewett… - Current issues in …, 2021 - mdpi.com
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Global seroprevalence and sociodemographic characteristics of Borrelia burgdorferi sensu lato in human populations: a systematic review and meta-analysis

Y Dong, G Zhou, W Cao, X Xu, Y Zhang, Z Ji… - BMJ Global …, 2022 - gh.bmj.com
Introduction Borrelia burgdorferi sensu lato (Bb) infection, the most frequent tick-transmitted
disease, is distributed worldwide. This study aimed to describe the global seroprevalence …

Clinical practice guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology …

PM Lantos, J Rumbaugh… - Clinical Infectious …, 2021 - academic.oup.com
This evidence-based clinical practice guideline for the prevention, diagnosis, and treatment
of Lyme disease was developed by a multidisciplinary panel representing the Infectious …

A review of post-treatment Lyme disease syndrome and chronic Lyme disease for the practicing immunologist

KH Wong, ED Shapiro, GK Soffer - Clinical reviews in allergy & …, 2022 - Springer
Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted
to humans through the bite of an infected Ixodes tick. The majority of patients recover without …

Advances in serodiagnostic testing for Lyme disease are at hand

JA Branda, BA Body, J Boyle… - Clinical Infectious …, 2018 - academic.oup.com
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing
protocol was established for serodiagnosis in 1994, involving an enzyme immunoassay …

Lyme borreliosis diagnosis: State of the art of improvements and innovations

M Guérin, M Shawky, A Zedan, S Octave, B Avalle… - BMC microbiology, 2023 - Springer
With almost 700 000 estimated cases each year in the United States and Europe, Lyme
borreliosis (LB), also called Lyme disease, is the most common tick-borne illness in the …

Lyme neuroborreliosis: clinical outcomes, controversy, pathogenesis, and polymicrobial infections

JC Garcia‐Monco, JL Benach - Annals of neurology, 2019 - Wiley Online Library
Lyme borreliosis is the object of numerous misconceptions. In this review, we revisit the
fundamental manifestations of neuroborreliosis (meningitis, cranial neuritis, and …

[HTML][HTML] Surveillance for Lyme disease after implementation of a revised case definition—United States, 2022

KJ Kugeler - MMWR. Morbidity and Mortality Weekly Report, 2024 - cdc.gov
Lyme disease, a tickborne zoonosis caused by certain species of Borrelia spirochetes, is the
most common vectorborne disease in the United States. Approximately 90% of all cases are …

Diagnostic testing for Lyme disease

T Kobayashi, PG Auwaerter - Infectious Disease Clinics, 2022 - id.theclinics.com
Diagnostic Testing for Lyme Disease - Infectious Disease Clinics Skip to Main Content Skip to
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Evaluation of modified two-tiered testing algorithms for Lyme disease laboratory diagnosis using well-characterized serum samples

A Pegalajar-Jurado, ME Schriefer… - Journal of Clinical …, 2018 - Am Soc Microbiol
Standard two-tiered testing (STTT) is the recommended algorithm for laboratory diagnosis of
Lyme disease (LD). Several limitations are associated with STTT that include low sensitivity …