Assessing and managing the metabolic syndrome in children and adolescents

MD DeBoer - Nutrients, 2019 - mdpi.com
The metabolic syndrome (MetS) is a group of cardiovascular risk factors that are associated
with insulin resistance and are driven by underlying factors, including visceral obesity …

Glomerular hyperfiltration: part 2—clinical significance in children

OC Adebayo, AB Nkoy, LP van den Heuvel… - Pediatric …, 2023 - Springer
Glomerular hyperfiltration (GHF) is a phenomenon that can occur in various clinical
conditions affecting the kidneys such as sickle cell disease, diabetes mellitus, autosomal …

Examining trends in prediabetes and its relationship with the metabolic syndrome in US adolescents, 1999–2014

AM Lee, CR Fermin, SL Filipp, MJ Gurka, MD DeBoer - Acta diabetologica, 2017 - Springer
Aims We sought to investigate temporal trends in prediabetes prevalence among US
adolescents using two definitions and evaluate relationships with obesity and a MetS …

Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity

M Wasniewska, G Pepe, T Aversa, S Bellone… - Children, 2023 - mdpi.com
Metabolic syndrome (MetS) is defined by a cluster of several cardio-metabolic risk factors,
specifically visceral obesity, hypertension, dyslipidemia, and impaired glucose metabolism …

Metabolic syndrome severity and risk of CKD and worsened GFR: the Jackson Heart Study

MD DeBoer, SL Filipp, SK Musani, M Sims… - Kidney and Blood …, 2018 - karger.com
Abstract Background/Aims: The metabolic syndrome (MetS), as assessed using
dichotomous criteria, is associated with increased risk of future chronic kidney disease …

Glomerular hyperfiltration is associated with liver disease severity in children with nonalcoholic fatty liver disease

T Yodoshi, AC Arce-Clachar, Q Sun, L Fei… - The Journal of …, 2020 - Elsevier
Objectives To determine the prevalence of renal impairment in a large cohort of youths with
histologically confirmed nonalcoholic fatty liver disease (NAFLD), and to determine its …

Serum creatinine levels and risk of incident type 2 diabetes mellitus or dysglycemia in middle-aged Japanese men: a retrospective cohort study

M Takeuchi, H Imano, I Muraki, Y Shimizu… - BMJ Open Diabetes …, 2018 - drc.bmj.com
Objective To assess the association between low serum creatinine levels and an increased
risk of type 2 diabetes mellitus and dysglycemia. Research design and methods We …

NAFLD and renal function in children: is there a genetic link?

A Di Sessa, S Guarino, AP Passaro… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Over the past decades, a large amount of both adult and pediatric data has
shown relationship between Nonalcoholic Fatty Liver Disease (NAFLD) and chronic kidney …

High triglyceride-glucose index with renal hyperfiltration and albuminuria in young adults: the Korea National Health and Nutrition Examination Survey (KNHANES V …

D Oh, SH Park, S Lee, E Yang, HY Choi… - Journal of Clinical …, 2022 - mdpi.com
Background: High triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance,
is associated with an increased risk of albuminuria in adults. However, the relationship …

[HTML][HTML] Insulin resistance underlies the elevated cardiovascular risk associated with kidney disease and glomerular hyperfiltration

MM Adeva-Andany, C Fernández-Fernández… - Reviews in …, 2020 - imrpress.com
The curve that describes the relationship between glomerular filtration rate (GFR) and
cardiovascular risk is U-shaped, indicating that both reduced GFR (kidney failure) and …