Signaling inflammation across the gut-brain axis

G Agirman, KB Yu, EY Hsiao - Science, 2021 - science.org
The brain and gastrointestinal tract are critical sensory organs responsible for detecting,
relaying, integrating, and responding to signals derived from the internal and external …

Bioelectronics for electrical stimulation: materials, devices and biomedical applications

Y Huang, K Yao, Q Zhang, X Huang, Z Chen… - Chemical Society …, 2024 - pubs.rsc.org
Bioelectronics is a hot research topic, yet an important tool, as it facilitates the creation of
advanced medical devices that interact with biological systems to effectively diagnose …

Miniature battery-free bioelectronics

V Nair, AN Dalrymple, Z Yu, G Balakrishnan… - Science, 2023 - science.org
Miniature wireless bioelectronic implants that can operate for extended periods of time can
transform how we treat disorders by acting rapidly on precise nerves and organs in a way …

Psychological stress in inflammatory bowel disease: Psychoneuroimmunological insights into bidirectional gut–brain communications

L Ge, S Liu, S Li, J Yang, G Hu, C Xu… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), mainly including ulcerative colitis (UC) and Crohn's
disease (CD), is an autoimmune gastrointestinal disease characterized by chronic …

Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19

F De Virgiliis, S Di Giovanni - Nature Reviews Neurology, 2020 - nature.com
COVID-19 is an infectious disease caused by the coronavirus SARS-CoV-2, which was first
reported in Wuhan, China, in December 2019 and has caused a global pandemic. Acute …

Strategies for precision vagus neuromodulation

U Ahmed, YC Chang, S Zafeiropoulos… - Bioelectronic …, 2022 - Springer
The vagus nerve is involved in the autonomic regulation of physiological homeostasis,
through vast innervation of cervical, thoracic and abdominal visceral organs. Stimulation of …

Transcutaneous auricular vagus nerve stimulation attenuates inflammatory bowel disease in children: a proof-of-concept clinical trial

B Sahn, K Pascuma, N Kohn, KJ Tracey… - Bioelectronic …, 2023 - Springer
Background Vagus nerve stimulation is an investigational anti-inflammatory therapy
targeting the nervous system to modulate immune activity. This study evaluated the efficacy …

A flexible protruding microelectrode array for neural interfacing in bioelectronic medicine

H Steins, M Mierzejewski, L Brauns, A Stumpf… - Microsystems & …, 2022 - nature.com
Recording neural signals from delicate autonomic nerves is a challenging task that requires
the development of a low-invasive neural interface with highly selective, micrometer-sized …

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

M Cracchiolo, MM Ottaviani, A Panarese… - Journal of Neural …, 2021 - iopscience.iop.org
Bioelectronic medicine (BM) is an emerging new approach for developing novel
neuromodulation therapies for pathologies that have been previously treated with …

Sympathetic activity regulates epithelial proliferation and wound healing via adrenergic receptor α2A

AS Ten Hove, S Mallesh, K Zafeiropoulou… - Scientific reports, 2023 - nature.com
Innervation of the intestinal mucosa by the sympathetic nervous system is well described but
the effects of adrenergic receptor stimulation on the intestinal epithelium remain equivocal …