Upstream analysis of alternative splicing: a review of computational approaches to predict context-dependent splicing factors

F Carazo, JP Romero, A Rubio - Briefings in Bioinformatics, 2019 - academic.oup.com
Alternative splicing (AS) has shown to play a pivotal role in the development of diseases,
including cancer. Specifically, all the hallmarks of cancer (angiogenesis, cell immortality …

[HTML][HTML] Genetic mechanisms regulating the host response during mastitis

V Asselstine, F Miglior, A Suárez-Vega… - Journal of dairy …, 2019 - Elsevier
Mastitis is a very costly and common disease in the dairy industry. The study of the
transcriptome from healthy and mastitic milk somatic cell samples using RNA-Sequencing …

DIS3L2 promotes progression of hepatocellular carcinoma via hnRNP U-mediated alternative splicing

S Xing, Z Li, W Ma, X He, S Shen, H Wei, ST Li, Y Shu… - Cancer research, 2019 - AACR
Abstract DIS3-like 3′-5′ exoribonuclease 2 (DIS3L2) degrades aberrant RNAs, however,
its function in tumorigenesis remains largely unexplored. Here, aberrant DIS3L2 expression …

Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles

TF Cardoso, R Quintanilla, A Castelló… - BMC genomics, 2018 - Springer
Background The identification of genes differentially expressed in the skeletal muscle of pigs
displaying distinct growth and fatness profiles might contribute to identify the genetic factors …

Divergence in morris water maze-based cognitive performance under chronic stress is associated with the hippocampal whole transcriptomic modification in mice

SH Jung, ML Brownlow, M Pellegrini… - Frontiers in molecular …, 2017 - frontiersin.org
Individual susceptibility determines the magnitude of stress effects on cognitive function. The
hippocampus, a brain region of memory consolidation, is vulnerable to stressful …

[HTML][HTML] Alternative Splicing Detection Tool—a novel PERL algorithm for sensitive detection of splicing events, based on next-generation sequencing data analysis

PG Adamopoulos, MC Theodoropoulou… - Annals of Translational …, 2018 - ncbi.nlm.nih.gov
Next-generation sequencing (NGS) can provide researchers with high impact information
regarding alternative splice variants or transcript identifications. However, the enormous …

Advances in alternative splicing identification: deep learning and pantranscriptome

F Shen, C Hu, X Huang, H He, D Yang… - Frontiers in Plant …, 2023 - frontiersin.org
In plants, alternative splicing is a crucial mechanism for regulating gene expression at the
post-transcriptional level, which leads to diverse proteins by generating multiple mature …

Profiling Novel Alternative Splicing within Multiple Tissues Provides Useful Insights into Porcine Genome Annotation

W Feng, P Zhao, X Zheng, Z Hu, J Liu - Genes, 2020 - mdpi.com
Alternative splicing (AS) is a process during gene expression that results in a single gene
coding for different protein variants. AS contributes to transcriptome and proteome diversity …

Sex‐biased gene expression in the frontal cortex of common marmosets (Callithrix jacchus) and potential behavioral correlates

VB Nogueira, DO Imparato, SJ de Souza… - Brain and …, 2018 - Wiley Online Library
Abstract Introduction The common marmoset (Callithrix jacchus), a small New World
monkey, has been widely used as a biological model in neuroscience to elucidate neural …

Profiling novel alternative splicing within multiple tissues puts insight into the porcine genome annotation

W Feng, P Zhao, X Zheng, JF Liu - 2019 - researchsquare.com
Background Alternative splicing (AS) is a process that mRNA precursor splices intron to form
the mature mRNA. AS plays important roles in contributing to transcriptome and proteome …