Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

The fetal origins of mental illness

BJS Al-Haddad, E Oler, B Armistead… - American journal of …, 2019 - Elsevier
The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

[HTML][HTML] An in vivo neuroimmune organoid model to study human microglia phenotypes

ST Schafer, AAF Mansour, JCM Schlachetzki, M Pena… - Cell, 2023 - cell.com
Microglia are specialized brain-resident macrophages that play crucial roles in brain
development, homeostasis, and disease. However, until now, the ability to model …

[PDF][PDF] Blood Markers in Detection of Autism.

T Stavridou, AM Driga, A Drigas - Int. J. Recent Contributions Eng …, 2021 - researchgate.net
The current paper gives a brief description of the relationship of biomarkers with autistic
spectrum disorder, we discuss autism, study the biomarkers which can be traced by medical …

Preterm or early term birth and risk of autism

C Crump, J Sundquist, K Sundquist - Pediatrics, 2021 - publications.aap.org
OBJECTIVES Preterm birth has been linked with increased risk of autism spectrum disorder
(ASD); however, potential causality, sex-specific differences, and association with early term …

Neuroinflammation in Parkinson's disease and its potential as therapeutic target

Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …

[HTML][HTML] Increasing comorbidities suggest that atopic dermatitis is a systemic disorder

PM Brunner, JI Silverberg, E Guttman-Yassky… - Journal of Investigative …, 2017 - Elsevier
Atopic dermatitis comorbidities extend well beyond the march to allergic conditions (food
allergy, asthma, allergic rhinitis, allergic conjunctivitis, and eosinophilic esophagitis) …

Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders

M Fiorentino, A Sapone, S Senger, SS Camhi… - Molecular autism, 2016 - Springer
Background Autism spectrum disorders (ASD) are complex conditions whose pathogenesis
may be attributed to gene–environment interactions. There are no definitive mechanisms …

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister - Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and …

A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude

A Saghazadeh, B Ataeinia, K Keynejad… - Journal of psychiatric …, 2019 - Elsevier
Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …