Novel insights into non-alcoholic fatty liver disease and dementia: insulin resistance, hyperammonemia, gut dysbiosis, vascular impairment, and inflammation
SY Cheon, J Song - Cell & Bioscience, 2022 - Springer
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterized by multiple
pathologies. The progression of dementia with NAFLD may be affected by various risk …
pathologies. The progression of dementia with NAFLD may be affected by various risk …
[HTML][HTML] Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer's disease: Evidence of ferroptosis
Iron dyshomeostasis is implicated in Alzheimer's disease (AD) alongside β-amyloid and tau
pathologies. Despite the recent discovery of ferroptosis, an iron-dependent form cell death …
pathologies. Despite the recent discovery of ferroptosis, an iron-dependent form cell death …
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer's disease
Alzheimer's disease (AD) is one of the foremost neurodegenerative diseases, characterized
by beta-amyloid (Aβ) plaques and significant progressive memory loss. In AD, astrocytes are …
by beta-amyloid (Aβ) plaques and significant progressive memory loss. In AD, astrocytes are …
Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine …
E Palacios, L Lobos-González, S Guerrero… - Journal of …, 2023 - Springer
Abstract Background Helicobacter pylori (Hp) infects the stomach of 50% of the world's
population. Importantly, chronic infection by this bacterium correlates with the appearance of …
population. Importantly, chronic infection by this bacterium correlates with the appearance of …
Cerebral fructose metabolism as a potential mechanism driving Alzheimer's disease
The loss of cognitive function in Alzheimer's disease is pathologically linked with
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …
Role of Nrf2 in synaptic plasticity and memory in Alzheimer's disease
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor that
reduces oxidative stress. When reactive oxygen species (ROS) or reactive nitrogen species …
reduces oxidative stress. When reactive oxygen species (ROS) or reactive nitrogen species …
High-sensitivity NH3 gas sensor using pristine graphene doped with CuO nanoparticles
A highly sensitive and selective NH3 gas sensor was developed based on single-layer
pristine graphene doped with copper (II) oxide (CuO) nanoparticles of a specific size. High …
pristine graphene doped with copper (II) oxide (CuO) nanoparticles of a specific size. High …
Expert insights: the potential role of the gut microbiome‐bile acid‐brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy
W Jia, C Rajani, R Kaddurah‐Daouk… - Medicinal research …, 2020 - Wiley Online Library
Recent epidemiological and molecular studies have linked the disruption of cholesterol
homeostasis to increased risk for developing Alzheimer's disease (AD). Emerging evidence …
homeostasis to increased risk for developing Alzheimer's disease (AD). Emerging evidence …
[HTML][HTML] A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Liver Disease (MASLD): Another matter to face through a holistic …
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most
common chronic hepatic disorder worldwide in both adults and children. It is well …
common chronic hepatic disorder worldwide in both adults and children. It is well …