Association between heavy metals, metalloids and metabolic syndrome: new insights and approaches

AC Martins, B Ferrer, AA Tinkov, S Caito… - Toxics, 2023 - mdpi.com
Metabolic syndrome (MetS) is an important public health issue that affects millions of people
around the world and is growing to pandemic-like proportions. This syndrome is defined by …

Environmental exposures influence multigenerational epigenetic transmission

E Klibaner-Schiff, EM Simonin, CA Akdis, A Cheong… - Clinical …, 2024 - Springer
Epigenetic modifications control gene expression and are essential for turning genes on and
off to regulate and maintain differentiated cell types. Epigenetics are also modified by a …

Anti-obesity and anti-inflammatory synergistic effects of green tea catechins and citrus β-cryptoxanthin ingestion in obese mice

K Nakadate, K Kawakami, N Yamazaki - International Journal of …, 2023 - mdpi.com
Chronic obesity causes various diseases, leading to an urgent need for its treatment and
prevention. Using monosodium-glutamate-induced obesity mice, the present study …

[HTML][HTML] Defining longitudinal trajectory of body mass index percentile and predicting childhood obesity: methodologies and findings in the Boston Birth Cohort

W Huang, AY Meir, B Olapeju, G Wang, X Hong… - Precision …, 2023 - journals.lww.com
Background: Overweight or obesity (OWO) in school-age childhood tends to persist into
adulthood. This study aims to address a critical need for early identification of children at …

Fetal exposure to toxic metals (mercury, cadmium, lead, and arsenic) via intrauterine blood transfusions

I Al-Saleh, H Alnuwaysir, R Al-Rouqi, H Aldhalaan… - Pediatric …, 2024 - nature.com
Abstract Background Intrauterine blood transfusions (IUBTs) are critical for treating fetal
anemia but may expose fetuses to toxic metals. This study assessed mercury (Hg), cadmium …

[HTML][HTML] Epigenetic toxicity of heavy metals− implications for embryonic stem cells

N Kim, D Filipovic, S Bhattacharya… - Environment International, 2024 - Elsevier
Exposure to heavy metals, such as cadmium, nickel, mercury, arsenic, lead, and hexavalent
chromium has been linked to dysregulated developmental processes, such as impaired …

Estimating causal effects of interventions on early-life environmental exposures using observational data

TJS Smith, AP Keil, JP Buckley - Current environmental health reports, 2023 - Springer
Abstract Purpose of Review We discuss how epidemiologic studies have used observational
data to estimate the effects of potential interventions on early-life environmental exposures …

Associations between paediatric obesity, chemical mixtures and environmental factors, in a national cross‐sectional study of Canadian children

R Dugandzic, N Konstantelos, Y Yu, E Lavigne… - Pediatric …, 2024 - Wiley Online Library
Background Whilst single chemical exposures are suspected to be obesogenic, the
combined role of chemical mixtures in paediatric obesity is not well understood. Objectives …

Prenatal exposure to metal mixtures and childhood temporal processing in the PROGRESS Birth Cohort Study: Modification by childhood obesity

JM Lane, FM Merced-Nieves, V Midya, SH Liu… - Science of the Total …, 2024 - Elsevier
Children are frequently exposed to various biological trace metals, some essential for their
development, while others can be potent neurotoxicants. Furthermore, the inflammatory and …

[HTML][HTML] Synergistic Effect of β-Cryptoxanthin and Epigallocatechin Gallate on Obesity Reduction

K Nakadate, K Kawakami, N Yamazaki - Nutrients, 2024 - mdpi.com
Chronic obesity is an alarmingly growing global public health concern, posing substantial
challenges for the prevention of chronic diseases, including hyperinsulinemia, type 2 …