Epigenetic modifications control gene expression and are essential for turning genes on and off to regulate and maintain differentiated cell types. Epigenetics are also modified by a …
K Nakadate, K Kawakami, N Yamazaki - International Journal of …, 2023 - mdpi.com
Chronic obesity causes various diseases, leading to an urgent need for its treatment and prevention. Using monosodium-glutamate-induced obesity mice, the present study …
Background: Overweight or obesity (OWO) in school-age childhood tends to persist into adulthood. This study aims to address a critical need for early identification of children at …
I Al-Saleh, H Alnuwaysir, R Al-Rouqi, H Aldhalaan… - Pediatric …, 2024 - nature.com
Abstract Background Intrauterine blood transfusions (IUBTs) are critical for treating fetal anemia but may expose fetuses to toxic metals. This study assessed mercury (Hg), cadmium …
Exposure to heavy metals, such as cadmium, nickel, mercury, arsenic, lead, and hexavalent chromium has been linked to dysregulated developmental processes, such as impaired …
Abstract Purpose of Review We discuss how epidemiologic studies have used observational data to estimate the effects of potential interventions on early-life environmental exposures …
R Dugandzic, N Konstantelos, Y Yu, E Lavigne… - Pediatric …, 2024 - Wiley Online Library
Background Whilst single chemical exposures are suspected to be obesogenic, the combined role of chemical mixtures in paediatric obesity is not well understood. Objectives …
Children are frequently exposed to various biological trace metals, some essential for their development, while others can be potent neurotoxicants. Furthermore, the inflammatory and …
K Nakadate, K Kawakami, N Yamazaki - Nutrients, 2024 - mdpi.com
Chronic obesity is an alarmingly growing global public health concern, posing substantial challenges for the prevention of chronic diseases, including hyperinsulinemia, type 2 …