Neurotrophic keratopathy

HS Dua, DG Said, EM Messmer, M Rolando… - Progress in retinal and …, 2018 - Elsevier
Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to
frank epithelial defect with or without stromal ulceration (melting) is associated with reduced …

In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Corneal nerves: structure, contents and function

LJ Müller, CF Marfurt, F Kruse, TMT Tervo - Experimental eye research, 2003 - Elsevier
This review provides a comprehensive analysis of the structure, neurochemical content, and
functions of corneal nerves, with special emphasis on human corneal nerves. A revised …

Neural basis of sensation in intact and injured corneas

C Belmonte, MC Acosta, J Gallar - Experimental eye research, 2004 - Elsevier
A renewed interest in the characteristics and neural basis of corneal and conjunctival
sensations is developing in recent years due to the high incidence of discomfort and altered …

Morphology of corneal nerves using confocal microscopy

L Oliveira-Soto, N Efron - Cornea, 2001 - journals.lww.com
Purpose. The aim of the current study was to evaluate the distribution and morphology of
corneal nerves as seen by means of white light confocal microscopy. Methods. This study …

Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites

A Guo, L Vulchanova, J Wang, X Li… - European Journal of …, 1999 - Wiley Online Library
The vanilloid receptor (VR1) protein functions both as a receptor for capsaicin and a
transducer of noxious thermal stimuli. To determine the expression and targetting of this …

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Current understanding of trigeminal ganglion structure and function in headache

K Messlinger, AF Russo - Cephalalgia, 2019 - journals.sagepub.com
Introduction The trigeminal ganglion is unique among the somatosensory ganglia regarding
its topography, structure, composition and possibly some functional properties of its cellular …

Architecture of human corneal nerves.

LJ Müller, GF Vrensen, L Pels… - … & visual science, 1997 - iovs.arvojournals.org
PURPOSE: The corneal innervation, mainly analyzed in light microscopical studies, has
been described as radially oriented stromal nerve bundles that ramify as leashes in the …

Ultrastructural organization of human corneal nerves.

LJ Müller, L Pels, GF Vrensen - Investigative ophthalmology & …, 1996 - iovs.arvojournals.org
PURPOSE: Although the human cornea is densely innervated, observations of the nerve
fiber distribution and ultrastructure are scarce. This study aimed to provide a detailed …