Biopharmaceutical industry is presently facing multiple economic, political and regulatory
challenges. The adoption of continuous bioprocessing is expected to partly alleviate these …

Continuous manufacturing in monoclonal antibody production has generated increased
interest due to its consistent quality, high productivity, high equipment utilization, and low …

Proposed herein is a systematic media design framework that combines multivariate
statistical approaches with in silico analysis of a genome-scale metabolic model of Chinese …

High titer and purity levels are key requirements for virus-based cancer and gene therapy
biopharmaceuticals. However, the task of removing enough host-cell DNA from therapeutic …

Affordability of biopharmaceuticals continues to be a challenge, particularly in developing
economies. This has fuelled advancements in manufacturing that can offer higher …

Production processes for biopharmaceuticals with mammalian cells have to provide a nearly
optimal environment to promote cell growth and product formation. Design and operation of …

Master the design and operation of perfusion cell cultures with this authoritative reference.
Discover the current state-of-the-art in the design and operation of continuous bioreactors …

Shifting resource base from fossil feedstock to renewable raw materials for production of
chemical products has opened up an area of novel applications of industrial biotechnology …

Continuous processing involves running unit operations of a process at steady state such
that production can continue for a considerable amount of time (typically in months). This is …

Analytical methods have been considered the “eyes” for development, characterization and
batch releasing of biotherapeutics over the past 40 years. One of the most powerful …