Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …

Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

Alzheimer's disease (AD) is a genetically complex, progressive and irreversible
neurodegenerative disorder of the brain which involves multiple associated etiological …

The natural β-carboline alkaloids display similarities with neurotransmitters that can be
favorably exploited to design bioactive and bioavailable drugs for Alzheimer's disease (AD) …

Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Evodiamine is a quinazolinocarboline alkaloid isolated from the fruits of traditional Chinese
herb Evodiae fructus. Previously, we identified N13-substituted evodiamine derivatives as …

The blood platelet plays an important role but often remains under‐recognized in several
vascular complications and associated diseases. Surprisingly, platelet hyperactivity and …

In this study, novel quinazolinone derivatives 7a-n were synthesized and evaluated against
metabolic enzymes including α-glycosidase, acetylcholinesterase, butyrylcholinesterase …

The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …