[HTML][HTML] Role of estrogen receptor α in aging and chronic disease

JVV Isola, S Ko, SR Ocañas… - Advances in geriatric …, 2023 - ncbi.nlm.nih.gov
Estrogen receptor alpha (ERα) plays a crucial role in reproductive function in both sexes. It
also mediates cellular responses to estrogens in multiple nonreproductive organ systems …

[HTML][HTML] Disruptions in reproductive health, sex hormonal profiles, and hypothalamic hormone receptors content in females of the C58/J mouse model of autism

I Barón-Mendoza, M Martínez-Marcial… - Hormones and …, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is characterized by differences in social
communication and interaction, as well as areas of focused interests and/or repetitive …

Sleep and Methylation of Estrogen Receptor Genes, ESR1 and GPER, in Healthy Middle-Aged and Older Women: Findings from the Women 40+ Healthy Aging …

ES Gardini, S Fiacco, L Mernone… - Nature and science of …, 2020 - Taylor & Francis
Purpose Sleep problems in middle-aged and older women are very common and have been
associated with menopause-related changes in estrogen levels. However, not all women …

Differential ESR1 Promoter Methylation in the Peripheral Blood—Findings from the Women 40+ Healthy Aging Study

ES Gardini, GG Chen, S Fiacco, L Mernone… - International journal of …, 2020 - mdpi.com
Background Estrogen receptor α (ERα) contributes to maintaining biological processes
preserving health during aging. DNA methylation changes of ERα gene (ESR1) were …

[HTML][HTML] Fasting/refeeding cycles prevent myocardial dysfunction and morphology damage in the spontaneously hypertensive rats

MF Pinotti, AM Matias, MM Sugizaki… - Arquivos Brasileiros …, 2018 - SciELO Brasil
Background: Caloric restriction is known to impair the cardiac function and morphology in
hypertrophied hearts of spontaneously hypertensive rats (SHR); however, the influence of …

A conserved mechanism of sirtuin signalling through steroid hormone receptors

HK Bayele - Bioscience Reports, 2019 - portlandpress.com
SIRT1 and orthologous sirtuins regulate a universal mechanism of ageing and thus
determine lifespan across taxa; however, the precise mechanism remains vexingly …

Memory function, neurological, and immunological biomarkers in allergic asthmatic mice intratracheally exposed to bisphenol A

TT Win-Shwe, R Yanagisawa, E Koike… - International journal of …, 2019 - mdpi.com
Bisphenol A (BPA) is a major constituent of plastic products, including epoxy resin
containers, mobile phones, dental sealants, as well as electronic and medical equipment …

The Anti-Senescence Effect and Mechanism of 17β-estradiol on Pelvic Organ Prolapse Derived Fibroblasts

J Cheng, Z Zhao, L Wang, J Wen, Y Miao, J Wu - 2023 - researchsquare.com
Background: Recently, low estrogen and the age at menopause as independent risk factors
for Pelvic Organ Prolapse (POP) were attracting high attention. In clinical practice, pre-/post …

大鼠ARC-BMA nesfatin-1 神经通路及对GD 神经元放电活动和胃运动的影响.

段秋霞, 栾晓, 郭菲菲, 孙向荣… - Progress in Modern …, 2017 - search.ebscohost.com
摘要目的: 探讨弓状核(ARC)-杏仁核(BMA) 间nesfatin-1 神经通路的构成及其对胃牵张敏感(GD)
神经放电活动和胃运动的影响. 方法: 逆行追踪结合免疫组化观察ARC-BMA 间nesfatin-1 …

[图书][B] Signature Search Method Development and Application in Drug Discovery

Y Duan - 2022 - search.proquest.com
This dissertation is about the development of gene expression signature (GES) search
methods and their application in drug discovery, specifically for promoting healthy aging …