Chemistry in continuous-flow continues to attract attention from the community of synthetic
organic chemists due to its now well-recognized benefits including, inter alia, quick reaction …

Major Cinchona alkaloids quinine, quinidine, cinchonine, and cinchonidine are available
chiral natural compounds (chiral pool). Unlike many other natural products, these alkaloids …

A new class of solid supported chiral imidazolidinone organocatalysts for the catalytic
reduction of imines with trichlorosilane has been developed. Polystyrene proved to be a …

A well-known squaramide-cinchonine organocatalyst was immobilized in a controlled way
onto three types of commercial porous glass beads EziG™(EziG OPAL, EziG Amber, and …

The asymmetric reduction of prochiral ketones and ketimines represents one of the most
important and practical chemical transformations toward the synthesis of valuable chiral …

This article is a history of an industrial–academic partnership that started almost two
decades ago and details the evolution of a relationship between a small academic research …

A concise overview of approaches to perform reductions of various functionalities including
aldehydes, ketones, esters, imines, nitriles, nitro groups, alkenes and alkynes under …

Cinchona-based chiral hyperbranched polymers (HBPs) were designed and successfully
synthesized via the Mizoroki-Heck (MH) coupling reaction. AB 2 and A 2 B-type chiral …

Chiral polyesters of cinchona alkaloid derivatives were synthesized via repetitive Mizoroki-
Heck (MH) coupling reaction. Under MH reaction conditions, 4-iodobenzoylquinine and 4 …

Yamamoto coupling polymerization has been used for the synthesis of polymeric chiral
organocatalysts. Cinchona squaramide derivatives with dibromophenyl moiety were …