High-resolution peripheral computed tomography (HR-pQCT) was developed to image bone
microarchitecture in vivo at peripheral skeletal sites. Since the introduction of HR-pQCT in …

Background People who have chronic kidney disease (CKD) have important changes to
bone structure, strength, and metabolism. Children experience bone deformity, pain, and …

Denosumab (Dmab), a monoclonal antibody against the receptor activator of nuclear factor-
κB (RANK) ligand (RANKL) which substantially suppresses osteoclast activity, has been …

Significant advances in immunosuppressive therapies have been made in renal
transplantation, leading to increased allograft and patient survival. Despite improvement in …

Objective Osteoporosis and fragility fractures represent serious complications for the solid
organ transplant population. The recommended osteoporosis therapy for organ recipients …

Bone and mineral disorders are common after organ transplantation. Osteoporosis post
transplantation is associated with increased morbidity and mortality. Pathogenesis of bone …

Objective The use of immunosuppressive agents, especially glucocorticoids, are associated
with increased risks of bone loss in kidney transplant patients. Denosumab, a potent …

Timelapse imaging using high-resolution peripheral quantitative computed tomography (HR-
pQCT) has emerged as a noninvasive method to quantify bone (re) modelling. However …

In this review the authors outline traditional antiresorptive pharmaceuticals, such as
bisphosphonates, monoclonal antibodies against RANKL, SERMs, as well as a drug with an …

Background Kidney transplant recipients (KTR) are at risk to lose bone mass. The trabecular
bone score (TBS) represents a recently developed parameter of lumbar spine trabecular …