[HTML][HTML] Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance

MM Rahman, MR Islam, S Akash… - Biomedicine & …, 2022 - Elsevier
Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments,
such as varieties of malignancies, neurological problems, and infectious illnesses …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

A thrombin‐activated peptide‐templated nanozyme for remedying ischemic stroke via thrombolytic and neuroprotective actions

Z Wang, Y Zhao, Y Hou, G Tang, R Zhang… - Advanced …, 2024 - Wiley Online Library
Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

A biomimetic drug delivery system by integrating grapefruit extracellular vesicles and doxorubicin-loaded heparin-based nanoparticles for glioma therapy

W Niu, Q Xiao, X Wang, J Zhu, J Li, X Liang, Y Peng… - Nano …, 2021 - ACS Publications
Existing nanoparticle-mediated drug delivery systems for glioma systemic chemotherapy
remain a great challenge due to poor delivery efficiency resulting from the blood brain …

Fruit‐Derived Extracellular‐Vesicle‐Engineered Structural Droplet Drugs for Enhanced Glioblastoma Chemotherapy

J Chen, J Pan, S Liu, Y Zhang, S Sha, H Guo… - Advanced …, 2023 - Wiley Online Library
Existing solid‐nanoparticle‐based drug delivery systems remain a great challenge for
glioblastoma chemotherapy due to their poor capacities in crossing the blood–brain …

Self‐Powered, Implantable, and Wirelessly Controlled NO Generation System for Intracranial Neuroglioma Therapy

S Yao, M Zheng, Z Wang, Y Zhao, S Wang… - Advanced …, 2022 - Wiley Online Library
Gas therapy is an emerging technology for improving cancer therapy with high efficiency
and low side effects. However, due to the existence of the gatekeeper of the blood–brain …

Highly bioactive zeolitic imidazolate framework-8–capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke

L He, G Huang, H Liu, C Sang, X Liu, T Chen - Science Advances, 2020 - science.org
Rational design of potent antioxidative agent with high biocompatibility is urgently needed to
treat ischemic reperfusion-induced ROS-mediated cerebrovascular and neural injury during …

[HTML][HTML] Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs

Y Li, Z Ye, H Yang, Q Xu - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Lipid nanoparticle (LNP)-based drug delivery systems have become the most clinically
advanced non-viral delivery technology. LNPs can encapsulate and deliver a wide variety of …

Charcot–Marie–Tooth neuropathies: current gene therapy advances and the route toward translation

M Stavrou, A Kagiava, I Sargiannidou… - Journal of the …, 2023 - Wiley Online Library
Abstract Charcot–Marie–Tooth (CMT) neuropathies are a group of genetically and
phenotypically heterogeneous disorders that predominantly affect the peripheral nervous …

Self-assembled lipid–prodrug nanoparticles

P Couvreur, S Lepetre-Mouelhi, E Garbayo… - Nature Reviews …, 2023 - nature.com
Nanomedicines suffer from poor drug loading and uncontrolled 'burst release'after
administration. Combining prodrug strategies with nanostructured carriers can help to …