The initiation and development of cariogenic (that is, caries-related) biofilms are the result of
the disruption of homeostasis in the oral microenvironment. There is a daily accumulation of …

Oral biofilms are a prominent cause of a wide variety of oral infectious diseases which are
still considered as growing public health problems worldwide. Oral biofilms harbor specific …

Conventional antibiotic therapies for biofilm-trigged oral diseases are becoming less
efficient due to the emergence of antibiotic-resistant bacterial strains. Antimicrobial …

Background Streptococcus mutans is a major contributor to dental caries due to its ability to
produce acid and survive in biofilms. Microbial resistance towards common antimicrobial …

Streptococcus mutans (S. mutans) and Candida albicans (C. albicans) are prominent
microbes associated with rapid and aggressive caries. In the present study, we investigated …

The persistence of microorganisms in the root canal system is one of the leading causes of
root canal treatment failure. Root canal anatomy is complex, and it is often a challenge to …

Photodynamic therapy (PDT) relies on the interactions between light, photosensitizers, and
tissue oxygen to produce cytotoxic reactive oxygen species (ROS), primarily singlet oxygen …

Backgrounds: Skin wounds are a kind of refractory disease frequently encountered in clinic,
which brings enormous burden to patients. Great efforts to address the dilemma of wound …

Objective To evaluate the efficacy of methylene blue (MB)-mediated antimicrobial
photodynamic therapy (aPDT) doped with potassium iodide (KI) against oral microcosms …

Antimicrobial photodynamic therapy (aPDT) shows promise in eliminating oral pathogens
without inducing microbial resistance. Yet, it faces limited biofilm penetration by the …