Dietary polyphenols represent a phytotherapeutic alternative for gut dysbiosis associated neurodegeneration: A Systematic review

A Chatterjee, S Kumar, SR Sarkar, R Halder… - The Journal of …, 2024 - Elsevier
Globally, neurodegeneration and cerebrovascular disease are common and growing
causes of morbidity and mortality. Pathophysiology of this group of diseases encompasses …

Biophysical and spectroscopical insights into structural modulation of species in the aggregation pathway of superoxide dismutase 1

VR Tomar, S Sharma, S Siddhanta… - Communications Chemistry, 2025 - nature.com
Abstract Superoxide dismutase 1 (SOD1) aggregation is implicated in the development of
Amyotrophic Lateral Sclerosis (ALS). Despite knowledge of the role of SOD1 aggregation …

Bisdemethoxycurcumin, a novel potent polyphenolic compound, effectively inhibits the formation of amyloid aggregates in ALS-associated hSOD1 mutant (L38R)

ZH Kouhi, B Seyedalipour, S Hosseinkhani… - International Journal of …, 2024 - Elsevier
Protein misfolding is a biological process that leads to protein aggregation. Anomalous
misfolding and aggregation of human superoxide dismutase (hSOD1) into amyloid …

[HTML][HTML] Recent studies on berberine and its biological and pharmacological activities

P Nadalin, YG Kim, SU Park - EXCLI journal, 2023 - ncbi.nlm.nih.gov
Benzylisoquinoline alkaloids (BIAs) are a variety of plant chemicals that consist of roughly
2,500 known compounds. Many BIAs are characterized by potent pharmacological activities …

Myricetin alleviates renal tubular epithelial-mesenchymal transition via NOX4/NF-κB/snail axis in diabetic nephropathy based on network pharmacology analysis

N Yuan, Y Chen, Y Yan, F Wang, X Xu, M Wang, J Diao… - Heliyon, 2024 - cell.com
Diabetic nephropathy (DN), a leading cause of end-stage renal disease, remains a
formidable challenge in diabetes management due to the complex nature of its …

Polymeric Materials as a Promising Platform for Suppressing Protein Aggregation Process

P Ghosh, A Mondal, P De - Current Indian Science, 2024 - benthamdirect.com
The idea of designing novel anti-amyloid therapeutic agents has generated a lot of scientific
interest and the potential for treating a variety of human pathophysiologies, such as …