Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class
with anti-inflammatory, analgesic, and antipyretic properties. Contrary to the action of many …

Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

Accurate prediction of the in vivo biopharmaceutical performance of oral drug formulations is
critical to efficient drug development. Traditionally, in vitro evaluation of oral drug …

The characterization and performance of stable amorphous solid dispersion systems were
evaluated in 40 research papers reporting active pharmaceutical ingredient (API) dissolution …

Many concepts of oral drug delivery are based on our comprehension of human
gastrointestinal physiology. Unfortunately, we tend to oversimplify the complex interplay …

The intraluminal conditions of the fed stomach are critical for drug release from solid oral
dosage forms and thus, often associated with the occurrence of food effects on oral …

Despite much progress in regulations to improve paediatric drug development, there
remains a significant need to develop better medications for children. For the design of oral …

Assessment of the disintegration, dissolution and drug release profiles of oral drug
formulations are routinely performed by subjecting them to standard pharmacopeial test …

The complex process of oral drug absorption is influenced by a host of drug and formulation
properties as well as their interaction with the gastrointestinal environment in terms of drug …

Lipid excipients are attracting interest from drug developers due to their performance, ease
of use, versatility and their potential to generate intellectual property through innovation in …