Characterization of pH-induced conformational changes in recombinant DENV NS2B-NS3pro
The increasing frequency of Dengue is a cause of severe epidemics and therefore demands
strategies for effective prevention, diagnosis, and treatment. DENV-protease is being …
strategies for effective prevention, diagnosis, and treatment. DENV-protease is being …
Biological detoxification of fumonisin by a novel carboxylesterase from Sphingomonadales bacterium and its biochemical characterization
Z Li, Y Wang, Z Liu, S Jin, K Pan, H Liu, T Liu… - International Journal of …, 2021 - Elsevier
Fumonisins have posed hazardous threat to human and animal health worldwide.
Enzymatic degradation is a desirable detoxification approach but is severely hindered by …
Enzymatic degradation is a desirable detoxification approach but is severely hindered by …
Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani
The enzyme pyridoxal kinase (PdxK) catalyzes the conversion of pyridoxal to pyridoxal-5′-
phosphate (PLP) using ATP as the co-factor. The product pyridoxal-5′-phosphate plays a …
phosphate (PLP) using ATP as the co-factor. The product pyridoxal-5′-phosphate plays a …
Structural and Biophysical properties of therapeutically important proteins Rv1509 and Rv2231A of Mycobacterium tuberculosis
N Rastogi, S Zarin, A Alam, GV Konduru… - International Journal of …, 2023 - Elsevier
Through comparative analyses using BLASTp and BLASTn of the 25 target sequences, our
research identified two unique post-transcriptional modifiers, Rv1509 and Rv2231A, which …
research identified two unique post-transcriptional modifiers, Rv1509 and Rv2231A, which …
Expression, purification, and biophysical characterization of recombinant MERS-CoV main (Mpro) protease
MERS-CoV main protease (M pro) is essential for the maturation of the coronavirus;
therefore, considered a potential drug target. Detailed conformational information is …
therefore, considered a potential drug target. Detailed conformational information is …
Structural and conformational behavior of MurE ligase from Salmonella enterica serovar Typhi at different temperature and pH conditions
MurE ligase is known to play a significant role in peptidoglycan biosynthesis. It catalyzes the
addition of meso-diaminopimelic acid to nucleotide precursor. The protein can adopt …
addition of meso-diaminopimelic acid to nucleotide precursor. The protein can adopt …
[HTML][HTML] Structural and Functional Characterization of Camelus dromedarius Glutathione Transferase M1-1
F Perperopoulou, N Poudel, AC Papageorgiou… - Life, 2022 - mdpi.com
Glutathione transferases (GSTs; EC. 2.5. 1.18) are a large family of multifunctional enzymes
that play crucial roles in the metabolism and inactivation of a broad range of xenobiotic …
that play crucial roles in the metabolism and inactivation of a broad range of xenobiotic …
[PDF][PDF] The Arabian Camel, Camelus dromedarius Interferon Alpha: Cloning, Expression in Escherichia coli, in vitro Refolding and Cytotoxicity on Triple Negative …
H Saeed, M Abdel-Fattah, A Eldoksh… - Pakistan Journal of …, 2021 - academia.edu
Expression of C. dromedarius IFNα cDNA in Escherichia coli revealed a fusion protein with a
weight of 22.5 kDa after induction of expression with IPTG for 5 h. The recombinant IFNα …
weight of 22.5 kDa after induction of expression with IPTG for 5 h. The recombinant IFNα …