Osteoarthritis (OA) is the most common form of arthritic disease, and a major cause of
disability and impaired quality of life in the elderly. OA is a complex disease of the entire …

The etiology of osteoporosis (OP) and osteoarthritis (OA) is multifactorial: both constitutional
and environmental factors, ranging from genetic susceptibility, endocrine and metabolic …

The material properties of cancellous bone from patients with osteoporosis (OP) or
osteoarthritis (OA) were determined and compared with normal controls. Samples were …

The aims of this study were to identify risk factors for hip fracture in men aged 50 years or
more. We identified 730 men with hip fracture from 14 centers from Portugal, Spain, France …

Objectives To determine the prevalence of clinically relevant falls‐related outcomes
according to pain status in older adults in the United States. Design Cross‐sectional …

Sclerostin, the product of the SOST gene, is a secreted inhibitor of Wnt signaling that is
produced by osteocytes to regulate bone formation. While it is often considered an osteocyte …

Osteoarthritis (OA) appears to be a mechanically driven but chemically mediated disease
process in which there is attempted (or aberrant) repair. Well established risk factors for OA …

OBJECTIVE To determine the material properties of the subchondral bone plate in patients
with osteoarthritis or osteoporosis. METHODS Femoral heads were obtained after surgical …

Objective To examine the association between osteoarthritis (OA), as defined by
radiographic evidence and self report, and osteoporotic fractures, falls, and bone loss in a …

Biochemical investigations into the pathogenesis of osteoarthritis have, for the last two
decades, concentrated on the mechanisms involved in the destruction of the articular …