Carbonic anhydrases (CAs, EC 4.2. 1.1) catalyse the interconversion between CO2 and
bicarbonate as well as other hydrolytic reactions. Among the six genetic families known to …

Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are zinc enzymes acting as efficient catalysts for the
reversible hydration of carbon dioxide to bicarbonate. 16 different α-CA isoforms were …

CO2 H2O^ HCO3 H(Eq. 1) The first carbonic anhydrase was purified from erythrocytes in
1933 (1) followed by the characterization of several mammalian isozymes that dominated …

Abstract Three‐dimensional (3D) domain swapping creates a bond between two or more
protein molecules as they exchange their identical domains. Since the term'3D domain …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread metalloenzymes all over the
phylogenetic tree, with at least 4 distinct gene families encoding for them. At least 16 …

Carbonic anhydrase, a zinc enzyme found in organisms from all kingdoms, catalyses the
reversible hydration of carbon dioxide and is used for inorganic carbon acquisition by …

Inhibitors and activators of the zinc enzyme carbonic anhydrase (CA, EC 4.2. 1.1) have a
large number of applications in therapy. Many types of such new derivatives have been …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread enzymes in all life kingdoms with
five distinct genetic families known to date, the α-, β-, γ-, δ-and ζ-CAs. With the exception of …