TGF-β signaling in metastatic colorectal cancer (mCRC): from underlying mechanism to potential applications in clinical development
X Li, Y Wu, T Tian - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …
TGF-β modulated pathways in colorectal cancer: new potential therapeutic opportunities
M Fasano, M Pirozzi, CC Miceli… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide, with 20%
of patients presenting with metastatic disease at diagnosis. TGF-β signaling plays a crucial …
of patients presenting with metastatic disease at diagnosis. TGF-β signaling plays a crucial …
Research progress of M13 bacteriophage-based biosensors
JS Moon, EJ Choi, NN Jeong, JR Sohn, DW Han… - Nanomaterials, 2019 - mdpi.com
Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure
have attracted considerable attention. These systems can detect a range of chemicals with …
have attracted considerable attention. These systems can detect a range of chemicals with …
Integrated transcriptomics and proteomics data analysis identifies CDH17 as a key cell surface target in colorectal cancer
KK Wong - Computational Biology and Chemistry, 2023 - Elsevier
Immunotherapy development against colorectal cancer (CRC) is hindered by the lack of cell
surface target highly expressed in cancer cells but with restricted presence in normal tissues …
surface target highly expressed in cancer cells but with restricted presence in normal tissues …
Different variables predict the outcome of patients with synchronous versus metachronous metastases of colorectal cancer
GA Colloca, A Venturino, D Guarneri - Clinical and Translational Oncology, 2020 - Springer
Purpose Timing of metastasis is a controversial prognostic factor for patients with metastatic
colorectal cancer (mCRC), as well as the performance of the common prognostic variables …
colorectal cancer (mCRC), as well as the performance of the common prognostic variables …
Antibody-drug conjugates of 7-ethyl-10-hydroxycamptothecin: sacituzumab govitecan and labetuzumab govitecan
W Dong, J Shi, T Yuan, B Qi, J Yu, J Dai, L He - European Journal of …, 2019 - Elsevier
Abstract Monoclonal antibody (mAb), cytotoxins, and linker technology are three essential
elements for developing a successful antibody-drug conjugate (ADC). In the research and …
elements for developing a successful antibody-drug conjugate (ADC). In the research and …
A filamentous bacteriophage targeted to carcinoembryonic antigen induces tumor regression in mouse models of colorectal cancer
P Murgas, N Bustamante, N Araya… - Cancer Immunology …, 2018 - Springer
Colorectal cancer is a deadly disease, which is frequently diagnosed at advanced stages,
where conventional treatments are no longer effective. Cancer immunotherapy has emerged …
where conventional treatments are no longer effective. Cancer immunotherapy has emerged …
In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of …
Carcinoembryonic antigen (CEA) is an antigen that is highly expressed in colorectal cancers
and widely used as a tumor marker. 131I and 90Y-radiolabeled anti-CEA monoclonal …
and widely used as a tumor marker. 131I and 90Y-radiolabeled anti-CEA monoclonal …
Genome-wide association study of serum tumor markers in Southern Chinese Han population
X Li, F Bai, X Wei, T Jin, C Li, Y Zhang, M Lin, X Zhou… - BMC cancer, 2022 - Springer
Abstract Background Serum indicators AFP, CA50, CA125, CA153, CA19-9, CEA, f-PSA,
SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide …
SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide …
[HTML][HTML] Electrospun biosensors for biomarker detection
J Zhou, J Zheng, C Wang, G Zhang, H Yang… - Colloid and Interface …, 2024 - Elsevier
Biosensors based on electrospun nanofibers have found extensive applications in the field
of biomarker detection. Nanofibers, owing to their advantages such as porosity, high surface …
of biomarker detection. Nanofibers, owing to their advantages such as porosity, high surface …