There are fundamental aspects of the control of metabolic homeostasis that are regulated
differently in males and females. This sex asymmetry represents an evolutionary paradigm …

In animal models, the physiological systems involved in metabolic homeostasis exhibit a sex
difference. Investigators often use male rodents because they show metabolic disease better …

The skeleton has recently emerged as an endocrine organ implicated in the regulation of
glucose and energy metabolism. This function of bone is mediated, at least in part, by …

Background: Conditions of excess androgen in women, such as polycystic ovary syndrome
(PCOS), often exhibit intergenerational transmission. One way in which the risk for PCOS …

Obesity and metabolic-related diseases, among which diabetes, are prominent public health
challenges of the 21st century. It is now well acknowledged that pollutants are a part of the …

Sex differences exist in the regulation of energy homeostasis. Better understanding of the
underlying mechanisms for sexual dimorphism in energy balance may facilitate …

The liver plays a crucial role in a variety of physiological processes. Sexual dimorphism is
markedly defined in liver disorders, such as fatty liver diseases and liver cancer, but barely …

Males and females have distinct propensities to develop obesity and its related
comorbidities, partially due to gonadal steroids. There are sex differences in hypothalamic …

Polycystic ovary syndrome (PCOS) is a common endocrinopathy that is associated with an
adverse metabolic profile including reduced postprandial thermogenesis. Although …

Endocrine disrupting chemicals (EDCs) are linked to the worldwide epidemic incidence of
metabolic disorders and fatty liver diseases, which affects quality of life and represents a …