[HTML][HTML] Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …
brain microstructure and to properties such as the density and shape of cells. Microstructure …
Time-dependent diffusion magnetic resonance imaging: measurement, modeling, and applications
R Ba, L Kang, D Wu - Journal of Zhejiang University-SCIENCE A, 2024 - Springer
Increasingly, attention is being directed towards time-dependent diffusion magnetic
resonance imaging (TDDMRI), a method that reveals time-related changes in the diffusional …
resonance imaging (TDDMRI), a method that reveals time-related changes in the diffusional …
[HTML][HTML] Frequency-dependent diffusion kurtosis imaging in the human brain using an oscillating gradient spin echo sequence and a high-performance head-only …
Measuring the time/frequency dependence of diffusion MRI is a promising approach to
distinguish between the effects of different tissue microenvironments, such as membrane …
distinguish between the effects of different tissue microenvironments, such as membrane …
A Magnetic Resonance Imaging‐Chemical Exchange Saturation Transfer (MRI‐CEST) Method for the Detection of Water Cycling across Cellular Membranes
E Di Gregorio, C Papi, L Conti, A Di Lorenzo… - Angewandte …, 2024 - Wiley Online Library
Water cycling across the membrane transporters is considered a hallmark of cellular
metabolism and it could be of high diagnostic relevance in the characterization of tumors …
metabolism and it could be of high diagnostic relevance in the characterization of tumors …
[HTML][HTML] Diffusion MRI with free gradient waveforms on a high-performance gradient system: Probing restriction and exchange in the human brain
The dependence of the diffusion MRI signal on the diffusion time carries signatures of
restricted diffusion and exchange. Here we seek to highlight these signatures in the human …
restricted diffusion and exchange. Here we seek to highlight these signatures in the human …
Improving MR cell size imaging by inclusion of transcytolemmal water exchange
The goal of the current study is to include transcytolemmal water exchange in MR cell size
imaging using the IMPULSED model for more accurate characterization of tissue cellular …
imaging using the IMPULSED model for more accurate characterization of tissue cellular …
Time‐dependent diffusivity and kurtosis in phantoms and patients with head and neck cancer
Purpose To assess the reliability of measuring diffusivity, diffusional kurtosis, and cellular‐
interstitial water exchange time with long diffusion times (100–800 ms) using stimulated …
interstitial water exchange time with long diffusion times (100–800 ms) using stimulated …
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI
Noninvasive mapping of cellular pathology can provide critical diagnostic and prognostic
information. Recent advances in diffusion magnetic resonance imaging enabled in vivo …
information. Recent advances in diffusion magnetic resonance imaging enabled in vivo …
Cellular Exchange Imaging (CEXI): Evaluation of a diffusion model including water exchange in cells using numerical phantoms of permeable spheres
R Gardier, JL Villarreal Haro… - Magnetic …, 2023 - Wiley Online Library
Purpose Biophysical models of diffusion MRI have been developed to characterize
microstructure in various tissues, but existing models are not suitable for tissue composed of …
microstructure in various tissues, but existing models are not suitable for tissue composed of …
Role of transmembrane water exchange in glioma invasion/migration: in vivo preclinical study by relaxometry at very low magnetic field
MR Ruggiero, H Ait Itto, S Baroni, S Pierre, J Boutonnat… - Cancers, 2022 - mdpi.com
Simple Summary Since the pioneering work of Damadian (1971), the longitudinal T1-
relaxation of nuclear magnetic resonance (NMR) has been reported to generate significant …
relaxation of nuclear magnetic resonance (NMR) has been reported to generate significant …