Flavonoids as potential antiviral agents for porcine viruses

X Zhang, S Chen, X Li, L Zhang, L Ren - Pharmaceutics, 2022 - mdpi.com
Flavonoids are types of natural substances with phenolic structures isolated from a variety of
plants. Flavonoids have antioxidant, anti-inflammatory, anticancer, and antiviral activities …

The baseline immunological and hygienic status of pigs impact disease severity of African swine fever

E Radulovic, K Mehinagic, T Wüthrich, M Hilty… - PLoS …, 2022 - journals.plos.org
African Swine Fever virus (ASFV) is a large double-enveloped DNA virus of the Asfarviridae
family that causes a lethal hemorrhagic disease in domestic pigs and wild boars. Since …

Gene expression of peripheral blood mononuclear cells and CD8+ T cells from gilts after PRRSV infection

E Lagumdzic, CPS Pernold, R Ertl, N Palmieri… - Frontiers in …, 2023 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-stranded RNA
virus, which emerged in Europe and USA in the late 1980s and has since caused huge …

A potent CD8 T-cell response may be associated with partial cross-protection conferred by an attenuated Chinese HP-PRRSV vaccine against NADC30-like PRRSV …

S Li, J Li, Y Tian, J Liu, J Zhu… - Journal of General …, 2023 - microbiologyresearch.org
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
devastating pathogens to the global swine industry. Many commercial PRRSV vaccines …

Testable candidate immune correlates of protection for porcine reproductive and respiratory syndrome virus vaccination

AR Kick, AF Grete, E Crisci, GW Almond, T Käser - Vaccines, 2023 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) is an on-going problem for
the worldwide pig industry. Commercial and experimental vaccinations often demonstrate …

Porcine reproductive and respiratory syndrome virus non-structural protein 4 cleaves guanylate-binding protein 1 via its cysteine proteinase activity to antagonize …

H Duan, H Dong, S Wu, J Ren, M Zhang, C Chen… - Veterinary …, 2022 - Springer
Porcine reproductive and respiratory syndrome (PRRS) is a highly infectious disease
caused by PRRS virus (PRRSV) that causes great economic losses to the swine industry …

Fitness adaptations of Japanese encephalitis virus in pigs following vector-free serial passaging

A Marti, A Nater, J Pego Magalhaes, L Almeida… - Plos …, 2024 - journals.plos.org
Japanese encephalitis virus (JEV) is a zoonotic mosquito-transmitted Flavivirus circulating in
birds and pigs. In humans, JEV can cause severe viral encephalitis with high mortality …

Development of a monoclonal antibody to pig CD69 reveals early activation of T cells in pig after PRRSV and ASFV infection

Y Tian, Y Hao, M Dong, S Li, D Wang, F Jiang, Q Wang… - Viruses, 2022 - mdpi.com
The CD69 molecule, as an early activation marker of lymphocytes, is often used to assess
the activation of cellular immunity. However, for pigs, an anti-pig CD69 antibody is not yet …

[HTML][HTML] Impact of Oil-in-Water Adjuvanted β-Glucan on Innate Immune Memory in Piglets

R Ardali, O Garcia-Nicolas, C Ollagnier… - Vaccines, 2024 - mdpi.com
The non-specific protective effects offered by the concept of “innate immune memory” might
represent a promising strategy to tackle early-life threatening infections. Here we tested the …